دانلود کتاب Essential Guide to Reading Biomedical Papers: Recognising and Interpreting Best Practice

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Essential Guide to Reading Biomedical Papers: Recognising and Interpreting Best Practice is an indispensable companion to the biomedical literature. This concise, easy-to-follow text gives an insight into core techniques and practices in biomedical research and how, when and why a technique should be used and presented in the literature.  Readers are alerted to common failures and misinterpretations that may evade peer review and are equipped with the judgment necessary to be properly critical of the findings claimed by research articles. This unique book will be an invaluable resource for students, technicians and researchers in all areas of biomedicine.

 

• Allows the reader to develop the necessary skills to properly evaluate research articles
• Coverage of over 30 commonly-used techniques in the biomedical sciences
• Global approach and application, with contributions from leading experts in diverse fields

Content:
Chapter 1 Philosophy of Science (pages 1–7): James Ladyman
Chapter 2 Ingredients of Experimental Design (pages 9–15): Nick Colegrave
Chapter 3 Statistics: A Journey that Needs a Guide (pages 17–26): Gordon Drummond
Chapter 4 Organ Bath Pharmacology (pages 27–38): Emma Robinson
Chapter 5 Small Vessel Myography (pages 39–48): Tomoko Kamishima and John M Quayle
Chapter 6 Mammalian Cell Cultures: The Example of Airway Epithelial Cell Cultures for Cystic Fibrosis Research (pages 49–58): Scott H Randell
Chapter 7 Electron Microscopy (TEM and SEM) (pages 59–65): Paul Verkade
Chapter 8 Fluorescence Microscopy (pages 67–76): Mark Jepson
Chapter 9 Intracellular ‘Sharp’ Microelectrode Recording (pages 77–84): Helena C Parkington and Harold A Coleman
Chapter 10 Single Electrode Voltage?Clamp (SEVC) (pages 85–93): Harold A Coleman and Helena C Parkington
Chapter 11 Patch Clamp Recording (pages 95–103): Neil Bannister and Phil Langton
Chapter 12 Production of Antibodies (pages 105–115): Elek Molnar
Chapter 13 Immunocytochemistry and Immunohistochemistry (pages 117–127): Elek Molnar
Chapter 14 Immunoprecipitation (IP) (pages 129–136): David Bates
Chapter 15 Immunoblotting (Western) (pages 137–145): Samantha F. Moore, Joshua S. Savage and Ingeborg Hers
Chapter 16 Applications of Green Fluorescent Protein (GFP) (pages 147–152): Mark Jepson
Chapter 17 Fluorescent Measurement of Ion Activity in Cells (pages 153–161): Helen Kennedy
Chapter 18 Detection of Exocytosis – Real Time (pages 163–171): Anja Teschemacher
Chapter 19 Viral Vector Transgenesis (pages 173–177): Anja Teschemacher
Chapter 20 Polymerase Chain Reaction (PCR) and Reverse Transcription (RT)?PCR (pages 179–186): Lucy F. Donaldson
Chapter 21 In Situ Hybridisation (ISH) (pages 187–192): Lucy F. Donaldson
Chapter 22 Methods of Interference (Antisense, siRNAs and Dominant Negative Mutations) (pages 193–202): Allison Fulford
Chapter 23 Transcriptome Analysis: Microarrays (pages 203–214): Charles Hindmarch
Chapter 24 Experimental Proteomics (pages 215–227): Thierry Le Bihan
Chapter 25 Behavioural Methodology (pages 229–240): Emma Robinson
Chapter 26 Genetically Modified Mouse Models (pages 241–246): Nina Balthasar
Chapter 27 Wireless Recording of Cardiovascular Signals (pages 247–252): Julian FR Paton and Fiona D McBryde
Chapter 28 Electrical Stimulation Methods (pages 253–260): Jon Wakerley
Chapter 29 Extracellular Recording (pages 261–269): Jon Wakerley
Chapter 30 Antidromic Identification (pages 271–278): Jon Wakerley
Chapter 31 Event?Triggered Averaging, Including Spike?Triggered Averaging (pages 279–284): Richard Apps
Chapter 32 Axonal Transport Tracing of CNS Pathways (pages 285–289): John Crabtree
Chapter 33 Cardiovascular Methods: General Considerations for Human Studies (pages 291–296): Erica A Wehrwein and Michael J Joyner
Chapter 34 Measuring Cardiac Output in Humans (pages 299–309): Erica A Wehrwein and Michael J Joyner
Chapter 35 Measuring Peripheral Blood Flow in Humans (pages 311–318): Erica A Wehrwein and Michael J Joyner