دانلود کتاب Fundamental Biomechanics in Bone Tissue Engineering (Synthesis Lectures on Tissue Engineering)

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Preface......Page 13
Background......Page 15
Bone Tissue Engineering......Page 17
Biomechanics vs. Bone Tissue Engineering......Page 18
Bibliography......Page 20
Introduction......Page 29
Cortical Bone......Page 30
Trabecular Bone......Page 32
Differences Between Anatomical Locations, Ages, and Genders......Page 33
Ultrastructure of Bone......Page 35
Constituents of Bone......Page 36
Differences Between Anatomical Locations, Ages, and Genders......Page 40
Differences in Tissue Architecture......Page 41
Bibliography......Page 43
Basic Concepts of Mechanics of Materials......Page 57
Elasticity......Page 58
Post-Yield Properties......Page 59
Failure......Page 60
Viscoelasticity......Page 61
Tensile/Compressive Test......Page 63
Torsion (Shear) Test......Page 67
3-Point and 4-Point Bending Test......Page 68
Progressive Loading......Page 70
Fracture Toughness Test......Page 71
Fatigue Test......Page 73
Viscoelastic Test......Page 74
Micro-Mechanical Testing Methodologies......Page 76
Nano-Indentation Methodologies......Page 78
Bibliography......Page 81
Introduction......Page 89
Mechanical Properties of Whole Bone......Page 90
Elastic Properties of Cortical and Trabecular Macroscopic Bone......Page 96
Post-Yield Properties of Cortical and Trabecular Macroscopic Bone......Page 102
Fracture Toughness of Cortical and Trabecular Macroscopic Bone......Page 104
Viscoelastic Behavior of Cortical and Trabecular Macroscopic Bone......Page 109
Fatigue Behavior of Cortical and Trabecular Macroscopic Bone......Page 111
Elastic Properties of Cortical and Trabecular Microscopic Bone......Page 112
Post-Yield Behavior of Cortical and Trabecular Microscopic Bone......Page 113
Mechanical Properties of Bone at the Sub-Microscopic Level......Page 114
Mechanical Properties of Hydroxyapatite and Collagen......Page 116
Physiological Response of Bone to Functional Loading......Page 117
Bibliography......Page 121
Introduction......Page 139
Determinants of the Mechanical Properties of Synthetic Polymers......Page 140
Examples of Synthetic Polymers for Bone Regeneration......Page 143
Determinants of the Mechanical Properties of Naturally derived Polymers......Page 145
Determinants of the Mechanical Properties of Ceramics......Page 148
Examples of Ceramic-Polymer Composites for Bone Regeneration......Page 149
Determinants of the Mechanical Properties of Metals......Page 150
Structural Requirements for Functional Scaffolds......Page 151
Determinants of Degradation......Page 152
Bibliography......Page 153
Introduction......Page 161
Torsional Test......Page 162
Tension......Page 165
Micro/Nano Indentation Tests......Page 166
In Vivo Stiffness Monitoring of Healing Bone......Page 167
Non-Invasive Measurement of Fracture Healing......Page 169
Dual-Energy X-Ray Absorptiometry (DEXA)......Page 170
Computed Tomography (CT) and Quantitative Computed Tomography (QCT)......Page 171
Numerical Evaluation of Fracture Healing......Page 173
Bibliography......Page 174
Biological Stages of Fracture Healing......Page 183
Inflammation......Page 184
Intramembranous Bone Formation in the Critical Sized Defect......Page 186
Torsional Properties......Page 189
Bending Properties......Page 192
Compressive Properties of Fracture Callus......Page 196
Bibliography......Page 200
Introduction......Page 207
Functional Architecture of Scaffold......Page 209
Non Biodegradable Scaffolds......Page 211
Osteoinductivity/Osteoconductivity......Page 212
Bioreactor: Biomimetic Environment for Bone Formation......Page 213
Cell Seeding......Page 214
Biological/Biochemical Environment......Page 215
Mechanosensation......Page 216
Authors' Biographies......Page 217