دانلود کتاب Gene Transfer Vectors for Clinical Application

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Content:
Series Page
Page ii

Copyright
Page iv

Contributors
Pages xi-xv

Preface
Pages xvii-xx
Theodore Friedmann

Methods in Enzymology
Pages xxi-l

Chapter one - General Principles of Retrovirus Vector Design
Pages 1-14
Tammy Chang, Jiing-Kuan Yee

Chapter Two - Strategies for Retrovirus-Based Correction of Severe, Combined Immunodeficiency (SCID)
Pages 15-27
Alain Fischer, Salima Hacein-Bey-Abina, Marina Cavazzana-Calvo

Chapter three - Retrovirus and Lentivirus Vector Design and Methods of Cell Conditioning
Pages 29-57
Samantha Cooray, Steven J. Howe, Adrian J. Thrasher

Chapter four - Analysis of the Clonal Repertoire of Gene-Corrected Cells in Gene Therapy
Pages 59-87
Anna Paruzynski, Hanno Glimm, Manfred Schmidt, Christof von Kalle

Chapter five - Developing Novel Lentiviral Vectors into Clinical Products
Pages 89-108
Anna Leath, Kenneth Cornetta

Chapter six - Lentivirus Vectors in ОІ-Thalassemia
Pages 109-124
Emmanuel Payen, Charlotte Colomb, Olivier Negre, Yves Beuzard, Kathleen Hehir, Philippe Leboulch

Chapter seven - Gene Therapy for Chronic Granulomatous Disease
Pages 125-154
Elizabeth M. Kang, Harry L. Malech

Chapter eight - Alternative Splicing Caused by Lentiviral Integration in the Human Genome
Pages 155-169
Arianna Moiani, Fulvio Mavilio

Chapter nine - Genotoxicity Assay for Gene Therapy Vectors in Tumor Prone Cdkn2a^{в€’/в€’} Mice
Pages 171-185
Eugenio Montini, Daniela Cesana

Chapter ten - Lentiviral Hematopoietic Cell Gene Therapy for X-Linked Adrenoleukodystrophy
Pages 187-198
Nathalie Cartier, Salima Hacein-Bey-Abina, Cynthia C. Bartholomae, Pierre BougnГЁres, Manfred Schmidt, Christof Von Kalle, Alain Fischer, Marina Cavazzana-Calvo, Patrick Aubourg

Chapter eleven - Retroviral Replicating Vectors in Cancer
Pages 199-228
Christopher R. Logg, Joan M. Robbins, Douglas J. Jolly, Harry E. Gruber, Noriyuki Kasahara

Chapter twelve - Adeno-Associated Virus Vectorology, Manufacturing, and Clinical Applications
Pages 229-254
Joshua C. Grieger, R. Jude Samulski

Chapter thirteen - Gene Delivery to the Retina: From Mouse to Man
Pages 255-274
Jean Bennett, Daniel C. Chung, Albert Maguire

Chapter fourteen - Generation of Hairpin-Based RNAi Vectors for Biological and Therapeutic Application
Pages 275-296
Ryan L. Boudreau, Beverly L. Davidson

Chapter Fifteen - Recombinant Adeno-Associated Viral Vector Reference Standards
Pages 297-311
Philippe Moullier, Richard O. Snyder

Chapter Sixteen - NIH Oversight of Human Gene Transfer Research Involving Retroviral, Lentiviral, and Adeno-associated Virus Vectors and the Role of the NIH Recombinant DNA Advisory Committee
Pages 313-335
Marina O'Reilly, Allan Shipp, Eugene Rosenthal, Robert Jambou, Tom Shih, Maureen Montgomery, Linda Gargiulo, Amy Patterson, Jacqueline Corrigan-Curay

Chapter Seventeen - Regulatory Structures for Gene Therapy Medicinal Products in the European Union
Pages 337-354
Bettina Klug, Patrick Celis, Melanie Carr, Jens Reinhardt

Author Index
Pages 355-376

Subject Index
Pages 377-385