دانلود کتاب Insect molecular biology and biochemistry

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Insect Molecular Biology And Biochemistry......Page 4
Copyright......Page 5
Contents......Page 6
Preface......Page 8
Contributors......Page 10
1 Insect Genomics......Page 12
1.2. Genome Sequencing......Page 13
1.3. Genome Analysis......Page 20
1.4. Proteomics......Page 27
1.5. Structural Genomics......Page 30
1.6. Metabolomics......Page 33
References......Page 34
2 Insect MicroRNAs: From Molecular Mechanisms to Biological Roles......Page 41
2.1. Introduction: The Big World of Small RNAs......Page 42
2.2. Biogenesis of miRNAs......Page 44
2.3. Mechanism of Action of miRNAs......Page 47
2.4. Identification of miRNAs in Insects......Page 49
2.5. Target Prediction......Page 51
2.6. miRNA Functions......Page 53
2.7. Conclusions and Perspectives......Page 61
References......Page 62
3 Insect Transposable Elements......Page 68
3.1. Introduction......Page 69
3.2. Classification and Transposition Mechanisms of Eukaryotic Transposable Elements......Page 70
3.3. Methods to Uncover and Characterize Insect TEs......Page 74
3.4. Diversity and Characteristics of Insect TEs......Page 76
3.5. Search for Active TEs in Insect Genomes......Page 80
3.6. Evolution of Insect TEs......Page 82
3.7. TEs in Insect Populations......Page 86
3.8. Impact of TEs in Insects......Page 87
3.9. Applications of Insect TEs......Page 89
3.10. Summary......Page 90
References......Page 91
4 Transposable Elements for Insect Transformation......Page 101
4.1. Introduction......Page 102
4.2. P Element Transformation......Page 103
4.3. Excision and Transposition Assays for Vector Mobility......Page 106
4.4. Transformation Marker Systems......Page 108
4.5. Transposon Vectors......Page 113
4.6. Transformation Methodology......Page 130
4.7. Summary......Page 133
References......Page 134
5.1. Introduction......Page 145
5.2. Cuticle Structure and Synthesis......Page 146
5.3. Classes of Proteins Found in Cuticles......Page 150
5.4. Genomic Information......Page 162
5.5. Interactions of Cuticular Proteins with Components of Cuticle......Page 164
5.6. Summary and Future Challenges......Page 171
References......Page 172
6 Cuticular Sclerotization and Tanning......Page 178
6.2. A Model for Cuticular Sclerotization......Page 179
6.3. Sclerotization (Tanning) Precursors......Page 181
6.4. Transport of Sclerotization Precursors to the Cuticle......Page 183
6.5. Cuticular Enzymes and Sclerotization......Page 184
6.6. Control of Sclerotization......Page 192
6.7. Cuticular Darkening......Page 194
6.9. Unsolved Problems......Page 196
References......Page 198
7.2. Chitin Structure and Occurrence......Page 204
7.3. Chitin Synthesis......Page 205
7.4. Chitin Degradation and Modification......Page 216
7.5. Chitin-Binding Proteins......Page 227
7.6. Chitin-Organizing Proteins......Page 230
7.7. Hormonal Regulation of Chitin Metabolism......Page 231
7.8. Chitin Metabolism and Insect Control......Page 232
7.9. Future Studies and Concluding Remarks......Page 236
References......Page 237
8.1. Introduction......Page 247
8.2. Diversity and Evolution of Insect CYP Genes......Page 250
8.3. P450 Enzymes......Page 256
8.4. P450 Functions......Page 267
8.5. Regulation of P450 Gene Expression......Page 295
8.6. Working with Insect P450 Enzymes......Page 299
8.7. Conclusion and Prospects......Page 306
References......Page 307
9.1. Historical Perspective......Page 328
9.2. Flight-Related Processes......Page 330
9.3. Apolipophorin III......Page 336
9.4. Lipophorin Receptor Interactions......Page 341
9.5. Other Lipid-Binding Proteins......Page 344
References......Page 348
10.1. Introduction and History......Page 357
10.2. Proteases in Eggs and Embryos......Page 358
10.3. Hemolymph Plasma Proteases......Page 359
10.4. Cellular Proteases......Page 363
10.5. Conclusions and Future Prospects......Page 366
References......Page 367
11 Biochemistry and Molecular Biology of Digestion......Page 376
11.2. Overview of the Digestive Process......Page 377
11.3. Midgut Conditions Affecting Enzyme Activity......Page 380
11.4. Digestion of Carbohydrates......Page 383
11.5. Digestion of Proteins......Page 393
11.6. Digestion of Lipids and Phosphates......Page 399
11.7. Microvillar Membranes......Page 401
11.8. The Peritrophic Membrane......Page 403
11.9. Organization of the Digestive Process......Page 408
11.10. Digestive Enzyme Secretion Mechanisms......Page 415
References......Page 417
12 Programmed Cell Death in Insects......Page 430
12.2. PCD, Apoptosis, Autophagy, or Necrosis?......Page 431
12.3. Historical Overview and Current Trends......Page 433
12.4. The Manduca Model......Page 434
12.5. The Drosophila Model......Page 442
12.6. Insights from Other Tissues......Page 449
12.7. Summary and Conclusions......Page 450
References......Page 451
13.1. Overview and Components......Page 461
13.2. Dpp, the BMP Pathway, and Gradients......Page 465
13.3. Other Developmental Contexts and Regulation of BMPs......Page 472
13.4. Activins and Non-Canonical TGF-β Signaling......Page 478
13.5. Evolution of TGF-β Signaling in Insects......Page 481
References......Page 482
14.2. Insect Immunology Background......Page 491
14.3. PAMP-Recognition Proteins in Insect Immunology......Page 492
14.4. Humoral Innate Immune Responses......Page 494
14.5. Cellular Innate Immune Responses......Page 508
14.6. Newly Emerging Topics in Insect Immunology......Page 511
14.7. Conclusion......Page 515
References......Page 516
15.1. Introduction......Page 524
15.2. The Drosophila Circadian Pacemaker......Page 527
15.3. Input Pathways to the Drosophila Circadian Pacemaker......Page 536
15.4. Neural Control of Drosophila Circadian Behavior......Page 544
15.5. Control of Circadian Rhythms in Non-Drosophilid Insects......Page 549
15.6. Conclusions......Page 551
References......Page 552
Index......Page 564