دانلود کتاب Macromolecular Crystallography: Deciphering the Structure, Function and Dynamics of Biological Molecules

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Front Matter....Pages i-xiv
Spatial and Temporal Organisation of Multiprotein Systems of Cell Regulation and Signalling: What Can We Learn from NHEJ System of Double-Strand Break Repair?....Pages 1-31
Co-translational Protein Processing, Folding, Targeting, and Membrane Insertion of Newly Synthesized Proteins....Pages 33-41
The Role of Multiple Sequence Repeat Motifs in the Assembly of Multi-protein Complexes....Pages 43-49
Cryoelectron Tomography or Doing Structural Biology In Situ....Pages 51-54
RuvBL1 and RuvBL2 and Their Complex Proteins Implicated in Many Cellular Pathways....Pages 55-63
The Structural Biology of Muscle: Spatial and Temporal Aspects....Pages 65-78
Molecular Basis of Allosteric Transitions: GroEL....Pages 79-86
Cell Signalling Through Covalent Modification and Allostery....Pages 87-92
Combining Cryo-EM and X-ray Crystallography to Study Membrane Protein Structure and Function....Pages 93-101
Molecular Mechanisms of DNA Polymerase Clamp Loaders....Pages 103-114
Electron Microscopy of Macromolecular Machines....Pages 115-123
Assembly and Function of the Signal Recognition Particle from Archaea....Pages 125-133
Structural Studies of the Functional Complexes of the 50S and 70S Ribosome, a Major Antibiotic Target....Pages 135-148
Proteopedia : Exciting Advances in the 3D Encyclopedia of Biomolecular Structure....Pages 149-161
Structure Analysis of Biological Macromolecules by Small-Angle X-ray Scattering....Pages 163-171
Structural Dynamics of the Vault Ribonucleoprotein Particle....Pages 173-182
Structural Dynamics of Picornaviral RdRP Complexes. Implications for the Design of Antivirals....Pages 183-193
Ribosomes: Ribozymes that Survived Evolution Pressures but Is Paralyzed by Tiny Antibiotics....Pages 195-208