دانلود کتاب MHC Molecules: Expression, Assembly and Function

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Front Matter....Pages i-xi
Major Histocompatibility Antigens: An Introduction....Pages 1-8
The Major Histocompatibility Complex Genes and their Transcriptional Regulation....Pages 9-34
TAP Peptide Transporters and Antigen Presentation....Pages 35-63
Molecular Chaperones in MHC Class I and Class II Biosynthesis and Assembly....Pages 65-71
Polypeptide Release from Lysosomes....Pages 73-82
Intracellular Trafficking of MHC Class II Molecules....Pages 83-96
The Role of HLA-DM in Class II Antigen Presentation....Pages 97-111
Crystallographic Analysis of Peptide Binding by Class I and Class II Major Histocompatibility Antigens....Pages 113-134
HLA and Disease: Molecular Basis....Pages 135-162
Epitope Prediction Algorithms for Class I MHC Molecules....Pages 163-180
Options for TCR Interactions: TCR Agonists, Antagonists and Partial Agonists....Pages 181-190
Role of Ligand Density in T Cell Reactions....Pages 191-206
Cooperative Recognition of MHC Class II:Peptide Complexes by the T Cell Receptor and CD4....Pages 207-228
Receptors for MHC Class I Molecules in Human Natural Killer Cells....Pages 229-241
The MHC in Host-Pathogen Evolution....Pages 243-260
Peptide-Mediated Regulation of Allergic Diseases....Pages 261-279
Genetic Modulation of Antigen Presentation....Pages 281-294
Back Matter....Pages 295-298