فهرست مطالب :
Content:
Inside Front Cover, Page ii
Front Matter, Page iii
Copyright, Page iv
Dedication, Page v
List of Contributors, Pages xxxvii-lv
Preface, Pages lvii-lviii, Bernard Amos
Immunoglobulin Structure: Diversity, Gene Duplication, and Domains, Pages 3-24, BRUCE A. CUNNINGHAM, PAUL D. GOTTLIEB, MOLLIE N. PFLUMM, GERALD M. EDELMAN
Three-Dimensional Structure of Immunoglobulins, Pages 25-32, D.R. DAVIES, V.R. SARMA, L.W. LABAW, E.W. SILVERTON, W.D. TERRY
Expansion and Contraction in the Evolution of Immunoglobulin Gene Pools, Pages 33-45, C. MILSTEIN, J. SVASTI
Structural Localization, Allelic Exclusion, and Linkage Relationships of Rabbit Allotypes, Pages 47-59, ROSE G. MAGE
Genetic Control of the Biosynthesis of IgG and IgM, Pages 61-70, A. NISONOFF, S.K. WILSON, A.C. WANG, H.H. FUDENBERG, J.E. HOPPER
Receptors for C3 on B Lymphocytes: Possible Role in the Immune Response, Pages 73-82, V. NUSSENZWEIG, C. BIANCO, P. DUKOR, A. EDEN
Subpopulations of Thymus Cells and Thymus-Derived Lymphocytes, Pages 83-93, MARTIN C. RAFF, HARVEY CANTOR
Immunoglobulins on Lymphocyte Membranes, Pages 95-106, B. PERNIS, M. FERRARINI, L. FORNI, L. AMANTE
Classes and Subclasses of Surface-Bound Immunoglobulins on Peripheral Blood Lymphocytes in Man, Pages 107-110, S.S. FROLAND, J.B. NATVIG
Immunoglobulin Determinants on the Surface of Antigen Binding T- and B-Lymphocytes in Mice, Pages 111-126, M.F. GREAVES, N.M. HOGG
Antiimmunoglobulin Antibody as Antigen. A Functional Approach to Receptor Immunoglobulin on Thymus Cells, Pages 127-139, GERT RIETHMÜLLER, ERNST-PETER RIEBER
Initiating Events in Immune Complex Injury, Pages 143-153, CHARLES G. COCHRANE
Release of Biologically Active Constituents from Blood Cells and its Role in Antibody-Mediated Tissue Injury, Pages 155-171, PETER M. HENSON
The Immunological Release of Chemical Mediators of Immediate Type Hypersensitivity from Human Lung, Pages 173-186, ROBERT P. ORANGE, K. FRANK AUSTEN
Cytochalasin B Reversibly Inhibits Phagocytosis by Human Blood Leukocytes, Pages 187-192, STEPHEN E. MALAWISTA
Actions and Interactions of Immunoglobulins in Immune Tissue Damage, Pages 193-212, GUY A. VOISIN
Cellular and Humoral Studies in Diseases with Heart-Reactive Antibodies, Pages 213-229, JOHN B. ZABRISKIE, STANLEY E. READ, ROBERT J. ELLIS
Affinity Lableing of Rabbit Antibodies with ɛ-4-Azido-2-Nitrophenyl Lysine, Pages 233-241, E.M. PRESS, G.W.J. FLEET, C.E. FISHER
Combining Sites of Anti-2,4-Dinitrophenyl Antibodies, Pages 243-251, HERMAN N. EISEN
Modification of Immunoglobulin Combining Sites, Pages 253-267, HENRY METZGER, BRUCE CHESEBRO, NORTIN M. HAULER, JOHN LEE, NEIL OTCHIN
Localization of Affinity Lable within the Primary Structure of γ2 Chain from Guinea Pig IgG(2), Pages 269-284, J.J. CEBRA, A. RAY, D. BENJAMIN, B. BIRSHTEIN
An Approach to the Mapping of Active Sites by Affinity Lableing, Pages 285-289, S.J. SINGER
Tentative Structure of Human IgM Immunoglobulin, Pages 291-307, FRANK W. PUTNAM, AKIRA SHIMIZU, CLAUDINE PAUL, TOMOTAKA SHINODA
Immunologcial Unresponsiveness: Cellular Kinetics and Interactions, Pages 311-322, WILLIAM O. WEIGLE, JACQUES M. CHILLER, GAIL S. HABICHT
Studies on the Influence of T Cells in Antibody Production, Pages 323-335, G.F. MITCHELL, R.I. MISHELL, L.A. HERZENBERG
Specificity of Helper Function, Pages 337-354, KLAUS RAJEWSKY, HELMUT POHLIT
Is There Evidence for a Non-Antigen Specific Diffusable Chemical Mediator from the Thymus-Derived Cell in the Initiation of the Immune Response?, Pages 355-368, R.W. DUTTON, R. FALKOFF, J.A. HIRST, M. HOFFMANN, J.W. KAPPLER, J.R. KETTMAN, J.F. LESLEY, D. VANN
Cell Interactions in the Graft-versus-Host Response, Pages 369-381, RICHARD ASOFSKY, HARVEY CANTOR, ROBERT E. TIGELAAR
Cytotoxic Lymphocytes as Effector Cells of Cell-Mediated Immunity, Pages 385-398, K.T. BRUNNER, J.-C. CEROTTINI
Migration Inhibitory Factor and Mediators of Cellular Hypersensitivity in Vitro, Pages 399-412, JOHN R. DAVID
Delayed Hypersensitivity and the Mechanism of Cellular Resistance to Infection, Pages 413-424, G.B. MACKANESS
Lymphocyte Response as a Model of Cell-Mediated Immunity, Pages 425-436, FRITZ H. BACH, DAVID C. ZOSCHKE, MARILYN L. BACH
Lymphocyte Effector Molecules: Mechanism of Human-Lymphotoxin Induced in Vitro Target Cell Destruction and Role in PHA-Induced Lymphocyte-Target Cell Cytolysis, Pages 437-445, G.A. GRANGER, T.W. WILLIAMS
Effect of Some Enzymes, Polysaccharides, and Lysosome-Active Drugs on Interaction of Immune Lymphocytes with Allogenic Target Cells, Pages 447-460, B.D. BRONDZ, A.E. SNEGIRÖVA, YU.A. RASSULIN, O.G. SHAMBORANT
Recent Studies on Manifestations of Delayed Cellular Hypersensitivity in Vitro and in Vivo, Pages 461-472, J. JOHANOVSKÝ, J. PEKÁREK, J. ŠVEJCAR, J. KREJČÍ, K. BARNET, A. CASTROVÁ, K. ČECH
Human Lymphocyte-Dependent Cytotoxic Antibody and Mechanisms of Target Cell Destruction in Vitro, Pages 473-482, JOHN R. WUNDERLICH, EUGENE B. ROSENBERG, JANET M. CONNOLLY
Specific Immune Response Genes of Guinea Pigs, Pages 485-494, BARUJ BENACERRAF, HARRY G. BLUESTEIN, IRA GREEN, LEONARD ELLMAN
Genetic Control of the Immune Response to Branched Synthetic Polypeptide Antigens in Inbred Mice, Pages 495-508, HUGH O. MCDEVITT, KATHLEEN B. BECHTOL, F. CARL GRUMET, GRAHAM F. MITCHELL, THOMAS G. WEGMANN
Cellular Basis of the Genetic Control of Immune Responses, Pages 509-528, G.M. SHEARER, EDNA MOZES, MICHAEL SELA
Genetic Regulation of the Function of Antibody-Producing Cells, Pages 529-545, G. BIOZZI, C. STIFFEL, D. MOUTON, Y. BOUTHILLIER, C. DECREUSEFOND
Genetic Control of Immune Responsiveness: Summary of Contributions by Discussants, Pages 547-549, HUGH O. MCDEVITT
Biochemistry of Complement, Pages 553-565, HANS J. MÜLLER-EBERHARD
Enzymes of the Complement System, Pages 567-577, NEIL R. COOPER
Biologically Active Fragments of Complement, Pages 579-595, IRWIN H. LEPOW
Ultrastructural Studies of Clq and of Complement-Membrane Interactions, Pages 597-608, MARGARET J. POLLEY
Genetic Polymorphism of Complement Components as a Probe of Structure and Function, Pages 609-624, CHESTER A. ALPER
A Model for the Regulation of Antibody Synthesis by Serum Antibody, Pages 627-636, JEAN-CLAUDE BYSTRYN, ISAAC SCHENKEIN, JONATHAN W. UHR
Antigen-Binding Receptors on Lymphoid Cells. Nature and Specificity of Receptors on Various Types of Immunocompetent Cells, Pages 637-651, WILLIAM E. PAUL, JOSEPH M. DAVIE
Regulation of the Ig Class Distribution in Anti-hapten Responses, Pages 653-664, O. MÄKELÄ, SAIJA KOSKIMIES, V.J. PASANEN
Recent Advances in Immunological Tolerance, Pages 665-677, G.J.V. NOSSAL
Immunology of Glomerulonephritis, Pages 681-687, FRANK J. DIXON, CURTIS B. WILSON Jr., HANS MARQUARDT
Immunological Phenomena in Rheumatoid Arthritis, Pages 689-697, I.M. ROITT
Immunodeficiency Diseases of Man, Pages 699-722, ROBERT A. GOOD, W. DOUGLAS BIGGAR, BYUNG H. PARK
Chemical Mediators of the Acute Inflammatory Response in Man, Pages 723-744, K. FRANK AUSTEN
Some Protein Disorders Associated with Neoplasms of Plasma Cells and Lymphocytes: Heavy Chain Diseases, Pages 745-760, EDWARD C. FRANKLIN
Virus–Antiviral Antibody Complexes, Pages 763-777, MICHAEL B.A. OLDSTONE, FRANK J. DIXON
Immunological Injury of Virus-Infected Cells by Antiviral Antibody and Complement, Pages 779-786, ABNER LOUIS NOTKINS
Interaction of Viruses with Human Lymphocytes, Pages 787-801, E. FREDERICK WHEELOCK, STEPHEN T. TOY, RUNE L. STJERNHOLM
Expression of Antigenic Determinants and Virus Synthesis in Mammalian Cells, Pages 803-814, A. PARAF, R. SCHERRER, M.A. MOYNE, L. LELIÈVRE, P. ROUZÈ, B. PRIGENT
Immunosuppression by Tumor Viruses: Effects of Leukemia Virus Infection on the Immune Response, Pages 815-829, HERMAN FRIEDMAN, WALTER S. CEGLOWSKI
Immunopathologic Mechanisms in the Dengue Shock Syndrome, Pages 831-838, PHILIP K. RUSSELL
Immunoglobulin Classes and Complement-Fixing Activity, Pages 841-848, TIBOR BORSOS
Biological Activities of IgG in Mammals, Pages 849-858, RUBÈN A. BINAGHI
Immunoglobulin E and Homocytotropic Properties, Pages 859-874, KIMISHIGE ISHIZAKA, TERUKO ISHIZAKA
Biological Significance of IgA Antibodies in Serum and Secretions, Pages 875-890, JOSEPH F. HEREMANS, JEAN-PIERRE VAERMAN
Metabolism of Immunoglobulins, Pages 891-903, THOMAS A. WALDMANN, WARREN STROBER, R. MICHAEL BLAESE
Tumor-Associated Antigens as Expressions of Chemically Induced Neoplasia and Their Involvement in Tumor-Host Interactions, Pages 907-920, R.W. BALDWIN, D. GLAVES, M.V. PIMM
Antigens in Virally Induced Tumors, Pages 921-938, HANS O. SJÖGREN, S.C. BANSAL
Cell-Mediated Immunity to Human Tumor Antigens, Pages 939-949, KARL ERIK HELLSTRÖM, INGEGERD HELLSTRÖM, HANS OLOV SJÖGREN, GLENN A. WARNER
Immunologic Response to Human Sarcomas: Relation of Antitumor Antibody to the Clinical Course, Pages 951-957, FREDERICK R. EILBER, DONALD L. MORTON
Experimental Basis and First Clinical Controlled Trials of Leukemia Active Immunotherapy, Pages 959-969, GEORGES MATHÉ
Old and New Facts and Speculations about Transplantation Antigens of Man, Pages 973-1025, RUGGERO CEPPELLINI
The (Relative) Importance of HL-A Matching in Kidney Transplantation, Pages 1027-1043, J.J. VAN ROOD
Mixed Lymphocyte Interaction: Disquisitions on a Popular Unknown, Pages 1045-1058, DARCY B. WILSON
Reconstitution: Grafting of Bone Marrow and Thymus, Pages 1061-1080, REBECCA H. BUCKLEY
Immunoregulation by Antibody, Pages 1081-1092, ROBERT S. SCHWARTZ
Stimulation: Selective Activation of Subpopulations of Antibody-Forming Cells, Pages 1093-1104, GREGORY W. SISKIND, THEODORE P. WERBLIN
Cellular Immunosorbents, Pages 1105-1114, HANS WIGZELL
Potentials for Immunologic Intervention in Cancer, Pages 1115-1129, RICHARD T. SMITH
Workshop 1 - Allotypes. I, Pages 1133-1138, S. DRAY, J.J. CEBRA
Workshop 2 - Antibacterial Immunity, Pages 1139-1142, DENNIS W. WATSON, FRANK M. COLLINS
Workshop 3a - Lymphocyte Activation. I, Pages 1143-1146, DARCY B. WILSON, GERALD WEISSMANN
Workshop 3b - Lymphocyte Activation. I, Pages 1147-1151, H.L. COOPER, H. GINSBURG
Workshop 4 - Cross Reactions between Microbial and Tissue Antigens, Pages 1153-1157, MELVIN H. KAPLAN, FELIX T. RAPAPORT
Workshop 5 - Lymphocyte Recirculation and its Immunological Significance, Pages 1159-1164, W.L. FORD, V.T. MARCHESI
Workshop 6 - The Fate of Antigens in Vivo, Pages 1165-1168, G.L. ADA, M.G. HANNA JR.
Workshop 7 - Blood Group Antigens, Pages 1169-1173, E.A. KABAT, W.M. WATKINS
Workshop 8 - Structural Requirements for Immunogenicity, Pages 1175-1179, P.H. MAURER, T.J. GILL
Workshop 9 - Ontogeny of the Immune Response, Pages 1181-1185, A.M. SILVERSTEIN, R. AUERBACH
Workshop 10 - Catabolism of Immunoglobulins, Pages 1187-1191, T.A. WALDMANN, V. GHETIE
Workshop 11 - Immunology of Gonorrhea and Syphilis, Pages 1193-1197, L.C. NORINS, J.N. MILLER
Workshop 12 - Antibodies to Enzymes, Pages 1199-1204, R. ARNON, B. CINADER
Workshop 13 - Radiation Effects on the Lymphoid Systems and Its Functions, Pages 1205-1209, D.W. VAN BEKKUM, E.P. CRONKITE
Workshop 14 - Nucleic Acids as Antigens, Pages 1211-1213, L. LEVINE, O.J. PLESCIA
Workshop 15 - Neutralization of Virus by Antibody, Pages 1215-1218, S. FAZEKAS DE ST. GROTH, A.L. NOTKINS
Workshop 16 - Granulocyte Functions in Immunological Reactions, Pages 1219-1222, P. WARD, L. LICHTENSTEIN
Workshop 17 - Immunologic Aging and Lymphoid Involution, Pages 1223-1225, ROY L. WALFORD, E.J. YUNIS
Workshop 18 - Immunology of Reproduction, Pages 1227-1232, E.J. BREYERE, S. SHULMAN
Workshop 19 - Tumor Antigens, Carcinogen Induced, Pages 1233-1236, R.W. BALDWIN, R.T. PREHN
Workshop 20 - Immune Deficiency Diseases: Dysgammaglobulinemia, Pages 1237-1240, D.S. ROWE, H.H. FUDENBERG
Workshop 21 - Immune Responses to Viral Antigens, Pages 1241-1247, J.A. BELLANTI, S.-E. SVEHAG
Workshop 22 - Allotypes. II, Pages 1249-1251, L.A. HERZENBERG, R.G. MAGE
Workshop 23 - Antibody Structure: Combining Site, Pages 1253-1256, H.N. EISEN, D. PRESSMAN
Workshop 24 - Lymphocyle Activation. III, Pages 1257-1261, JOOST J. OPPENHEIM, STELLA KNIGHT
Workshop 25a - Cell Cooperation in the Immune Response. I, Pages 1263-1266, H.N. CLAMAN, G.J. THORBECKE
Workshop 25b - Cell Cooperation in the Immune Response. II, Pages 1267-1270, G. CUDKOWICZ, J.S. HASKILL
Workshop 26 - Immune Deficiency Disease: Thymic Aplasia, Pages 1271-1278, R.A. GOOD, H.H. WORTIS
Workshop 27 - Macrophages: Role in Resistance to Microbial Parasitism, Pages 1279-1282, G.B. MACKANESS, S. RAFFEL
Workshop 28 - Adjuvants, Pages 1283-1285, R.G. WHITE, W. BRAUN
Workshop 29 - Kinetics and Thermodynamics of Antibody–Antigen Interactions, Pages 1287-1289, A. SEHON, F. HAUROWITZ
Workshop 30 - Cellular Kinetics of the Immune Response, Pages 1291-1293, EDWIN S. LENNOX, T. MAKINODAN
Workshop 31 - Immune Capabilities of Germ-Free Animals, Pages 1295-1297, M. POLLARD, A. NORDIN
Workshop 32 - Homocytotropic Antibodies, Pages 1299-1303, S.G.O. JOHANSSON, Z. OVARY
Workshop 33 - Phylogenetic Aspects of Immunity, Pages 1305-1310, W.H. HILDEMANN, L.W. CLEM
Workshop 34 - Human Histocompatibility Antigens, Pages 1311-1314, J.B. DAUSSET, W.F. BODMER
Workshop 35 - Immunologic Assay of Biologically Active Materials, Pages 1315-1318, E. HABER, F.C. GREENWOOD
Workshop 36 - Autoimmune Diseases: Genetics, Mechanisms, and Diagnostic Approaches, Pages 1319-1321, H.H. FUDENBERG, H.R. HOLMAN
Workshop 37 - Immunological Activation of the Kinin-Forming System, Pages 1323-1328, K. FRANK AUSTEN, ELMER L. BECKER
Workshop 38 - New Immunohistochemical Methods, Pages 1329-1332, S. AVRAMEAS, E.E. SERCARZ
Workshop 39 - Immunoglobulin Biosynthesis, Pages 1333-1337, B.A. ASKONAS, M.D. SCHARFF
Workshop 40 - Immunopathogenesis of Glomerulonephritis, Pages 1339-1342, F.J. DIXON, G.A. ANDRES
Workshop 41 - Tumor Antigens: Relationship to Histocompatibility Antigens, Pages 1343-1345, J.L. FAHEY, I. HELLSTROM
Workshop 42 - Immunosuppression, Pages 1347-1350, G.L. FLOERSHEIM, G.W. SANTOS
Workshop 43 - Virus–Lymphocyte Interactions, Pages 1351-1353, T.C. MERIGAN JR., E.F. WHEELOCK
Workshop 44 - Antibody Structure: Ig Diversity, Pages 1355-1359, F.W. PUTNAM, W.D. TERRY
Workshop 45 - Idiotypic Antibody, Pages 1361-1363, M. POTTER, H.G. KUNKEL
Workshop 46a - Membrane- Associated Antigens of Lymphoid Cells. I, Pages 1365-1368, M. SCHLESINGER, M. RAFF
Workshop 46b - Membrane-Associated Antigens of Lymphoid Cells. II, Pages 1369-1372, R.W. DUTTON, M.F. GREAVES
Workshop 47 - Histocompatibility Antigens: Characterization, Pages 1373-1377, R.A. REISFELD, M. EDIDIN
Workshop 48 - Macrophages: Their Role in the Induction of Immunity, Pages 1379-1382, M. FELDMAN, E.R. UNANUE
Workshop 49 - Immunosuppression: Antilymphocyte Serum, Pages 1383-1387, H. BALNER, E.M. LANCE, A.P. MONACO
Workshop 50 - Genetic Control of Immune Responsiveness, Pages 1389-1393, H.O. MCDEVITT, I. GREEN
Workshop 51 - Transfer of Immunity with Cell-Free Extracts, Pages 1395-1401, H.S. LAWRENCE, M. FISHMAN
Workshop 52 - Theories of Antibody Formation, Pages 1403-1405, M. COHN, M. SIMONSEN
Workshop 53 - Immunological Disorders of Inbred Strains of Mice, Pages 1407-1409, N. TALAL, J.H.L. PLAYFAIR
Workshop 54 - Chemotaxis of Leucocytes: Immunologic and Nonimmunologic Factors, Pages 1411-1415, E. SORKIN, P.A. WARD
Workshop 55 - Thymic Hormones, Pages 1417-1419, A. WHITE, R.H. LEVEY
Workshop 56 - Immunity to Parasitic Infections, Pages 1421-1426, S. COHEN, E.H. SADUN
Workshop 57 - Biochemistry of Complement, Pages 1427-1434, M.M. MAYER, R.A. NELSON Jr.
Workshop 58 - Separation of Different Functional Classes of Small Lymphocytes, Pages 1435-1438, H. WIGZELL, L. WOFSY
Workshop 59 - Bacterial Endotoxins, Pages 1439-1443, L. CHEDID, O. WESTPHAL
Workshop 60 - Cytotoxic Activities of Lymphocytes, Pages 1445-1448, B.H. WAKSMAN, K.T. BRUNNER
Workshop 61 - Tumor Antigens: Virus Induced, Pages 1449-1453, V. DEFENDI, E. KLEIN
Workshop 62 - Antibody Structure and Evolution, Pages 1455-1458, N. HILSCHMANN, H.M. GREY
Workshop 63 - In Vitro Models of Delayed Hypersensitivity, Pages 1459-1462, J.-C. CEROTTINI, D.C. DUMONDE
Workshop 64 - Relationships among Major Histocompatibility Systems, Pages 1463-1465, F.H. BACH, D.C. SHREFFLER
Workshop 65 - Immunological Tolerance, Pages 1467-1470, W.O. WEIGLE, N.A. MITCHISON
Workshop 66a - The Origin of Antigen-Sensitive Lymphocytes. I, Pages 1471-1475, N.L. WARNER, E. MOLLER
Workshop 66b - The Origin of Antigen-Sensitive Lymphocyte. II, Pages 1477-1480, G.F. MITCHELL, R.B. TAYLOR
Workshop 67 - Secretory Immunoglobulins, Pages 1481-1486, T.B. TOMASI JR., J.J. CEBRA
Workshop 68 - Immunologic Derangements Caused by Chronic Viral Infections, Pages 1487-1491, A.C. ALLISON, M.B.A. OLDSTONE
Workshop 69 - Homogeneous Antibody and Myeloma Proteins with Antibody Activity, Pages 1493-1497, R.M. KRAUSE, E. HABER
Workshop 70 - Ultrastructure of Immunoglobulin and Ag-Ab Complexes, Pages 1499-1503, S.E. SVEHAG, N.M. GREEN
Workshop 71 - Antibody Synthesis in Vitro, Pages 1505-1509, T.N. HARRIS, R. MISHELL
Workshop 72 - Antigenic Competition, Pages 1511-1514, F.L. ADLER, G. MÖLLER
Workshop 73 - Purification and Characterization of Allergens, Pages 1515-1518, MERRILL W. CHASE, ARTHUR MALLEY
Workshop 74 - Complement and Disease States, Pages 1519-1522, F.S. ROSEN, N.R. COOPER
Workshop 75 - Histology of the Immune Response, Pages 1523-1525, A.H. COONS, R.T. MCCLUSKEY
Workshop 76 - Soluble Mediators of Delayed Hypersensitivity, Pages 1527-1532, F. VALENTINE, J.R. DAVID
Workshop 77 - Pathogenesis of Runting Syndrome, Pages 1533-1536, M. SIMONSEN, R.M. ASOFSKY
Workshop 78 - Allergic Release of Amines from Cells, Pages 1537-1539, A.G. OSLER, R.P. SIRAGANIAN
Workshop 79 - Established Lymphoblastoid Cell Lines, Pages 1541-1543, R. CEPPELLINI, B.O. OSUNKOYA, P.R. GLADE
Workshop 80 - Immunological Enhancement, Pages 1545-1547, N. KALISS, F.W. FITCH
Index, Pages 1549-1554