دانلود کتاب Receptor biology

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Content: Title Page
Copyright
Dedication
Table of Contents
Acknowledgments
Part I: Introduction
Chapter 1: Introduction
1.1 Receptors and Signaling
1.2 Types of Receptors and Hormones
1.3 Receptors Are the Chemical Expression of Reality
Chapter 2: The Origins of Chemical Thinking
2.1 Overview of Early Pharmacological History
2.2 Modern Pharmacology
2.3 Phylogenetics of Signaling
Part II: Fundamentals
Chapter 3: Membranes and Proteins
3.1 Membranes
3.2 The Nature and Function of Proteins
Chapter 4: Hormones as First Messengers
4.1 Hormones and Cellular Communication 4.2 Types of Hormones4.3 Vertebrate Hormones and Transmitters
4.4 Analgesics and Venoms as Receptor Ligands
Chapter 5: Receptor Theory
5.1 The Materialization of Receptors
5.2 Receptor Mechanisms
5.3 Binding Theory
5.4 Visualizing Receptor Structure and Function
5.5 Proteomics Approaches to Receptor Efficacy
5.6 Physical Factors Affecting Receptor Binding
Part III: Receptor Types and Function
Chapter 6: Transduction I: Ion Channels and Transporters
6.1 Introduction
6.2 Small Molecule Channels
6.3 Transporters
6.4 Major Intrinsic Proteins
6.5 Ligand-Gated Ion Channels Chapter 7: Transduction II: G-Protein-Coupled Receptors7.1 Introduction
7.2 Families of G-Protein-Coupled Receptors
7.3 Transduction Mechanisms
7.4 The Major Families of G Protein-Coupled Receptors
Chapter 8: Transduction III: Receptor Kinases and Immunoglobulins
8.1 Protein Kinases
8.2 Receptors for Cell Division and Metabolism
8.3 Receptor Serine/Threonine Kinases
8.4 The Guanylyl Cyclase Receptor Subfamily --
Natriuretic Peptide Receptors
8.5 Non-Kinase Molecules --
LDL Receptors
8.6 Cell-Cell Contact Signaling
8.7 Immune System Receptors, Antibodies, and Cytokines Chapter 9: Transduction IV: Nuclear Receptors9.1 Introduction
9.2 Genomic Actions of Nuclear Receptors
9.3 Actions of Receptor Antagonists
9.4 Non-Traditional Actions of Steroid-Like Hormones and Their Receptors
Part IV: Applications
Chapter 10: Signaling Complexity
10.1 Introduction
10.2 Experimental Determination of Signaling Cascades
10.3 Transduction across the Membrane
10.4 Complexity in Cross Talk --
Roles of PIP3, Akt, and PDK1
10.5 Role in Cancer
10.6 Signaling Mediated by Gas Molecules
Chapter 11: Cellular Interactions in Development
11.1 Introduction 11.2 The Origins of Multicellularity11.3 The Origin of Symmetry and Axes
11.4 Fertilization and Organization of the Multicellular Body Plan
11.5 Differentiation of Triploblastic Embryos --
Organogenesis
11.6 Programmed Cell Death (Apoptosis)
Chapter 12: Receptor Mechanisms in Disease Processes
12.1 Genetic Basis for Receptor Function
12.2 Receptor Pathologies
12.3 Signaling Mutations Leading to Cancer
Chapter 13: Receptors and the Mind
13.1 Origins of Behavior
13.2 Nervous Systems
13.3 Animal Memory: Invertebrates
13.4 Animal Memory: Vertebrates