دانلود کتاب The Immunological Barriers to Regenerative Medicine

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Front Matter....Pages i-xiii
Front Matter....Pages 1-1
Mechanisms of Immune Rejection of Stem Cell-Derived Tissues: Insights From Organ Transplantation....Pages 3-36
The Immunogenicity of Embryonic Stem Cells and Their Differentiated Progeny....Pages 37-48
Interaction of Embryonic Stem Cells with the Immune System....Pages 49-67
The Role of NK Cells and T Cells in the Rejection of Embryonic Stem Cell-Derived Tissues....Pages 69-76
Mitigating the Risk of Immunogenicity in the Pursuit of Induced Pluripotency....Pages 77-94
Thymic Involution: A Barrier or Opportunity for Cell Replacement Therapy?....Pages 95-108
Front Matter....Pages 109-109
Construction of Human Embryonic Stem Cell Banks: Prospects for Tissue Matching....Pages 111-128
Generation of Histocompatible Tissues via Parthenogenesis....Pages 129-146
Prospects for Designing ‘Universal’ Stem Cell Lines....Pages 147-173
The Immunosuppressive Properties of Adult Stem Cells: Mesenchymal Stem Cells as a Case Study....Pages 175-197
Front Matter....Pages 199-199
The Immunogenicity of Stem Cells and Thymus-Based Strategies to Minimise Immune Rejection....Pages 201-223
The Induction of Mixed Chimerism Using ES Cell-Derived Hematopoietic Stem Cells....Pages 225-255
Prospects for the Induction of Transplant Tolerance Using Dendritic Cells....Pages 257-278
Strategies for the Induction of Tolerance with Monoclonal Antibodies....Pages 279-295
Induction of Immunological Tolerance to Transgene Products....Pages 297-311
Addressing the Challenge of Autoimmunity in the Treatment of Diabetes with Stem Cells....Pages 313-329
Back Matter....Pages 331-334