دانلود کتاب Blood-Brain Barrier

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Front Matter ....Pages i-xiii
An Overview of the Blood-Brain Barrier (Tatiana Barichello, Allan Collodel, Rodrigo Hasbun, Rodrigo Morales)....Pages 1-8
Methods of Delivering Molecules Through the Blood-Brain Barrier for Brain Diagnostics and Therapeutics (Brian M. Kopec, Kavisha R. Ulapane, Mario E. G. Moral, Teruna J. Siahaan)....Pages 9-43
Culturing of Rodent Brain Microvascular Endothelial Cells for In Vitro Modeling of the Blood-Brain Barrier (Malgorzata Burek, Carola Y. Förster)....Pages 45-54
In Vitro BBB Models: Working with Static Platforms and Microfluidic Systems (Mohammad A. Kaisar, Vinay V. Abhyankar, Luca Cucullo)....Pages 55-70
In Vitro Cell Models of the Human Blood-Brain Barrier: Demonstrating the Beneficial Influence of Shear Stress on Brain Microvascular Endothelial Cell Phenotype (Keith D. Rochfort, Philip M. Cummins)....Pages 71-98
Transepithelial/Transendothelial Electrical Resistance (TEER) to Measure the Integrity of Blood-Brain Barrier (Balaji Srinivasan, Aditya Reddy Kolli)....Pages 99-114
Cell-Penetrating Peptides as Theranostics Against Impaired Blood-Brain Barrier Permeability: Implications for Pathogenesis and Therapeutic Treatment of Neurodegenerative Disease (Swapna Bera, Anirban Bhunia)....Pages 115-136
Microbial Translocation of the Blood-Brain Barrier (Charles T. Spencer, Mireya G. Ramos Muniz)....Pages 137-161
Transport Across the Choroid Plexus: How to Culture Choroid Plexus Cells and Establish a Functional Assay System (Sen Takeda, Keishi Narita)....Pages 163-173
Drosophila as a Model to Study the Blood-Brain Barrier (Cameron R. Love, Brigitte Dauwalder)....Pages 175-185
Zebrafish (Danio rerio) as a Viable Model to Study the Blood-Brain Barrier (Tianzhi Yang, Shuhua Bai)....Pages 187-196
Evans Blue-Albumin as a Marker to Evaluate Blood-Brain Barrier Integrity in Neonatal and Adult Rodents (Fabricia Petronilho, Julia L. Goldman, Tatiana Barichello)....Pages 197-203
Experimental Tools to Study the Regulation and Function of the Choroid Plexus (Isabel Gonçalves, Telma Quintela, Ana Catarina Duarte, Peter Hubbard, Graça Baltazar, Christian Schwerk et al.)....Pages 205-230
Techniques for Evaluating Efflux Transport of Radiolabeled Drugs and Compounds from the Cerebrospinal Fluid Across the Blood-Cerebrospinal Fluid Barrier (Shin-ichi Akanuma, Yoshiyuki Kubo, Ken-ichi Hosoya)....Pages 231-248
In Vivo Analysis to Study Transport Across the Blood-Retinal Barrier (Yoshiyuki Kubo, Shin-ichi Akanuma, Ken-ichi Hosoya)....Pages 249-265
Increasing BBB Permeability via Focused Ultrasound: Current Methods in Preclinical Research (Dallan McMahon, Charissa Poon, Kullervo Hynynen)....Pages 267-297
Evaluation of Blood–Brain Barrier Permeability and Integrity in Juvenile Rodents: Dynamic Contrast-Enhanced (DCE), Magnetic Resonance Imaging (MRI), and Evans Blue Extravasation (Trish Domi, Faraz Honarvar, Andrea Kassner)....Pages 299-314
Recording Leukocyte Rolling and Adhesion on Meningeal Vessels by Intravital Microscopy (Aline Silva de Miranda, Thiago Macedo Cordeiro, Milene Alvarenga Rachid, Antônio Lúcio Teixeira)....Pages 315-327
Molecular Imaging of Blood–Brain Barrier Permeability in Preclinical Models Using PET and SPECT (Vijayasree V. Giridharan, Tatiana Barichello, Sudhakar Selvaraj)....Pages 329-342
Biomarkers for Microvascular Proteins Detection: Blood–Brain Barrier Injury and Damage Measurement (Pavani Sayana, Jean Pierre Oses, Tatiana Barichello, Vijayasree V. Giridharan)....Pages 343-363
Back Matter ....Pages 365-367