دانلود کتاب Carbohydrate-Based Vaccines and Immunotherapies

توضیحاتی در مورد کتاب به زبان اصلی :

The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments.

With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances.

Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include:

• Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi

• Using adjuvants to improve immunogenicity and/or immunological properties of vaccines

• Choosing and designing proper adjuvants for specific targets

• Abnormal carbohydrates expressed by tumors

• Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy

• Clinical trials results for synthetic cancer vaccines

• Glycoengineering of cell surface carborhydrates and its anticancer applications

• Using cell surface carbohydrates for disease diagnosis

A single, convenient source of state-of-the-art information from leading authorities in the field, Carbohydrate-Based Vaccines and Immunotherapies is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.Content:
Chapter 1 Glycobiology and Immunology (pages 1–53): Udayanath Aich and Kevin J. Yarema
Chapter 2 Preparation of Glycoconjugate Vaccines (pages 55–88): Wei Zou and Harold J. Jennings
Chapter 3 Adjuvants for Protein? and Carbohydrate?Based Vaccines (pages 89–115): Bruno Guy
Chapter 4 Carbohydrate?Based Antibacterial Vaccines (pages 117–166): Robert A. Pon and Harold J. Jennings
Chapter 5 Carbohydrate?Based Antiviral Vaccines (pages 167–193): Benjamin M. Swarts and Zhongwu Guo
Chapter 6 Carbohydrate?Based Antiparasitic Vaccines (pages 195–214): Faustin Kamena, Xinyu Liu and Peter H. Seeberger
Chapter 7 Carbohydrate?Based Antifungal Vaccines (pages 215–226): Magdia De Jesus, Liise?Anne Pirofski and Arturo Casadevall
Chapter 8 Cancer?Associated and Related Glycosphingolipid Antigens (pages 227–262): Steven B. Levery
Chapter 9 Semisynthetic and Fully Synthetic Carbohydrate?Based Cancer Vaccines (pages 263–311): Therese Buskas, Pamela Thompson and Geert?Jan Boons
Chapter 10 Glycoengineering of Cell Surface Sialic Acid and Its Application to Cancer Immunotherapy (pages 313–331): Zhongwu Guo
Chapter 11 Therapeutic Cancer Vaccines: Clinical Trials and Applications (pages 333–366): Hans H. Wandall and Mads A. Tarp
Chapter 12 Carbohydrates as Unique Structures for Disease Diagnosis (pages 367–394): Kate Rittenhouse?Olson