دانلود کتاب Catalytic Asymmetric Friedel–Crafts Alkylations

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Cover......Page 1
Catalytic Asymmetric Friedel–Crafts Alkylations......Page 4
ISBN: 978-3-527-32380-7......Page 5
Foreword......Page 6
Contents......Page 8
Preface......Page 14
List of Contributors......Page 16
1.1 Introduction......Page 18
1.2 General Aspects and Historical Background......Page 20
1.3 Catalytic Enantioselective FC Reactions: An Introduction......Page 22
References......Page 31
2.1 Chelating a,b-Unsaturated Compounds......Page 34
2.2 Simple a,b-Unsaturated Substrates......Page 66
2.3 Nitroalkenes......Page 84
References......Page 111
3.1 Aldehydes/Ketones......Page 118
3.2 Imines......Page 136
References......Page 157
4.1 Introduction......Page 162
4.2 Allylic Alkylations......Page 164
4.3 Metallo-Catalyzed Hydroarylation of Allenes......Page 177
References......Page 181
5 Nucleophilic Substitution on Csp3 Carbon Atoms......Page 184
5.1 Ring-Opening of Epoxides......Page 185
5.2 Direct Activation of Alcohols......Page 198
References......Page 215
6.1 Introduction......Page 220
6.2 Early Studies......Page 221
6.3 Rh(I)-Catalyzed Enantioselective Hydroarylation of Iminoarenes......Page 224
6.4 Pt(II)-Catalyzed Enantioselective Hydroarylation of Alkenylindoles......Page 231
6.5 Au(I)-Catalyzed Enantioselective Hydroarylation of Allenylindoles......Page 234
6.6 Conclusions and Outlook......Page 236
6.7 Experimental: Selected Procedures......Page 237
References......Page 238
7.1 Introduction......Page 240
7.2 Total Synthesis of Indole-Containing Compounds......Page 241
7.3 Total Synthesis of Pyrrole-Containing Compounds......Page 257
7.4 Friedel–Crafts Alkylation of Furan Derivatives in Total Synthesis......Page 264
7.5 Friedel–Crafts Alkylation of Arenes in Total Synthesis......Page 266
7.6 Asymmetric Synthesis of Natural Products Based on Diastereoselective Friedel–Crafts Reactions......Page 270
References......Page 285
8.1 Introduction......Page 288
8.2 Green Chemistry and the Friedel–Crafts Reaction......Page 289
8.3 Heterogeneous Catalysts for the Friedel–Crafts Reaction......Page 292
8.4 Large Scale Hydrocarbon Processing......Page 295
References......Page 303
Index......Page 306