دانلود کتاب Chemotherapy: Volume 7 Cancer Chemotherapy I

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Front Matter....Pages i-xii
Advances in Cancer Chemotherapy....Pages 1-17
Experimental Basis of Cancer Chemotherapy....Pages 19-50
New Leads Towards Antitumor Selectivity in Therapeutics....Pages 51-55
An Experimental Approach to Increase Selective Tumour Toxicity of Methotrexate....Pages 57-68
Alterations in Intracellular Cyclic AMP as a Potential Form of Anti-Tumour Chemotherapy....Pages 69-74
The Drug-Carrier Potential of Liposomes in Cancer Chemotherapy....Pages 75-82
Significance of Prostaglandins in Tumour Growth....Pages 83-88
Oestrogen Binding as a Predictive Test for DMBA-Induced Tumour Response to Tamoxifen Therapy....Pages 89-94
Action of Anticancer Drugs on the Cell Cycle. Chromosome Damage and Differential Stage Sensitivity....Pages 95-103
Adriamycin Metabolism in Man....Pages 105-111
Pharmacokinetics of Anticancer Drugs....Pages 113-117
Pharmacokinetics and Metabolism of Anticancer Drugs....Pages 119-127
The Activity of New Drugs Against Mouse Tumours....Pages 129-147
Platinum Complexes as Anti-Cancer Drugs....Pages 149-157
Streoptozotocin, Chlorozotocin and Related Nitrosourea Antitumour Agents....Pages 159-166
Analogues and Metabolites of Cyclophosphamide....Pages 167-181
ICRF 159 and Other Bisdioxopiperazines....Pages 183-186
Biological Basis of Radiosensitization by Hypoxic-Cell Radiosensitizers....Pages 187-206
Bleomycin and Radiotherapy....Pages 207-210
Experience with ICRF 159 and Radiotherapy in Combination in the Treatment of Soft Tissue Sarcomas....Pages 211-214
Metronidazole (Flagyl) in Cancer Radiotherapy....Pages 215-222
Possibilities of the Human Tumour/Nude Mouse System in Cancer Chemotherapy Research....Pages 223-223
Chemotherapy of Transplantable Colon Tumours in Mice....Pages 225-232
Utilization of Nitrosamine-Induced Tumors as Models for Cancer Chemotherapy....Pages 233-238
The Production of Osteolytic Substances by Human Breast Tumours....Pages 239-241
The Biological Basis of Combination Chemotherapy....Pages 243-248
Combination Chemotherapy of Advanced Gastrointestinal Carcinoma....Pages 249-254
Combination Chemotherapy in Breast and Lung Cancer....Pages 255-269
Chemotherapy of CNS Tumors....Pages 271-275
Nitrosoureas: Clinical and Experimental Considerations in the Treatment of Brain Tumors....Pages 277-283
Effect of CCNU on Survival, Objective Remissions and Free Interval in Patients with Malignant Gliomas....Pages 285-288
Intracavitary Glioma Chemotherapy....Pages 289-293
Screening of Enzyme Inhibitors with Potential Antitumor Activity....Pages 295-298
Recent Experience with Microbial Systems and Cancer Cells in Vitro in the Screening for Antitumor Antibiotics....Pages 299-302
Problems Related to the Detection of Activity of Antitumor Antibiotics....Pages 303-308
Attempts to Overcome Methotrexate Resistance: The Value of Drug Resistant Cell Lines....Pages 309-314
In Vitro Mutagenesis by Anti-Cancer Drugs....Pages 315-322
In Vitro Systems Using Micro-Organisms for Detection of Carcinogenic Agents....Pages 323-326
In Vitro Screening of Cytotoxic Substances Using Different Tumour Cells....Pages 327-333
In Vitro Methods for Use in Drug Metabolism Studies....Pages 335-340
Some Problems in the Use of Short Term Cultures of Human Tumours for in Vitro Screening of Cytotoxic Drugs....Pages 341-350
Combination of Corynebacterium Parvum and Cytostatic Drugs in Disseminated Human Cancers....Pages 351-354
Radiotherapy and Chemotherapy in Acute Leukaemia Related to Fatal Infection During Remission....Pages 355-358
The Target Cell of Immunosuppressive Agents....Pages 359-360
Immunological Aspects of Anti-Cancer Drugs....Pages 361-361
Back Matter....Pages 363-364