دانلود کتاب Chromosomal Alterations: Methods, Results and Importance in Human Health

فهرست مطالب :

Front Matter....Pages i-xxiv
Human Chromosomes: Structural and Functional Aspects....Pages 1-20
DNA Lesions Induced by Ionizing Radiation....Pages 21-38
Effects of Ultraviolet Radiation on DNA....Pages 39-53
Double Strand Break Repair Mechanisms in Mammalian Cells....Pages 55-65
Backup Pathways of Nonhomologous End Joining May Have a Dominant Role in the Formation of Chromosome Aberrations....Pages 67-85
Targeted and Non-Targeted Induction of Chromosomal Rearrangements After Exposure to Ionizing Radiation....Pages 87-98
DNA Methylation Damage: Formation, Repair and Biological Consequences....Pages 99-121
Adducts, Sister-Chromatid Exchanges and Mutations Following Benzo[ a ]pyrene Exposure: a Review of Quantitative Data Followed by Some Considerations Regarding Risk....Pages 123-143
Analysis of DNA Double-Strand Breaks by Means of γ -H2AX Foci....Pages 145-160
Comet Assay....Pages 161-176
Origin of Chromosome Aberrations: Mechanisms....Pages 177-199
Chromatin Structure and the Formation of Chromosomal Alterations....Pages 201-209
Role of Chromatin Structure and Activity in the Induction of Chromosomal Aberrations....Pages 211-224
A Biomedical Perspective of Telomere Structure and Function....Pages 225-240
Cytokinesis-Block Micronucleus Assay: a Comprehensive “Cytome” Approach for Measuring Chromosomal Instability, Mitotic Dysfunction and Cell Death Simultaneously in One Assay....Pages 241-255
In Vivo Rodent Micronucleus Assay....Pages 257-270
Sister-Chromatid Exchanges....Pages 271-283
Fluorescence in Situ Hybridisation....Pages 285-299
The CAB and S&S Systems, and an Approach Towards the Classification of Complex Chromosome Exchanges....Pages 301-314
Aberration Patterns and Cell Cycle Progression Following Exposure of Lymphocytes to the Alkylating Agent Trenimon....Pages 315-324
Cytogenetic Analysis and Occupational Health....Pages 325-340
Biological Dosimetry....Pages 341-350
Statistical Methods for Biological Dosimetry....Pages 351-370
Retrospective Biological Dosimetry by FISH....Pages 371-380
Chromosomal Aberrations in Astronauts....Pages 381-396
Internet Information System and Literature Database on Biomedical Activities of Electromagnetic Fields: Cancer and Cytogenetic Effects....Pages 397-409
Interpreting Studies on Magnetic Fields and the Risk of Childhood Leukaemia: an Ongoing Challenge....Pages 411-426
Cytogenetic and Carcinogenic Effects of Exposure to Radiofrequency Radiation....Pages 427-469
Radiofrequency Radiation and Replication Studies....Pages 471-478
Chromosome Analysis in Cancer Patients: Applications and Limitations....Pages 479-493
Chromosomal Aberration in Peripheral Blood Lymphocytes of Healthy Subjects and Risk of Cancer....Pages 495-504
Back Matter....Pages 505-515