دانلود کتاب Fractures of the Pelvis and Acetabulum

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Front Matter....Pages i-xvii
Front Matter....Pages 1-1
The Origin and Development of Neural Crest-Derived Melanocytes....Pages 3-26
MITF....Pages 27-49
MITF....Pages 51-69
Melanocytes and the Transcription Factor Sox10....Pages 71-80
Human Cutaneous Pigmentation....Pages 81-100
Melanocyte Distribution and Function in Human Skin....Pages 101-115
Front Matter....Pages 117-117
Altered Signal Transduction in Melanoma....Pages 119-147
BRN2 in Melanocytic Cell Development, Differentiation, and Transformation....Pages 149-167
The Dynamic Roles of Cell-Surface Receptors in Melanoma Development....Pages 169-181
Familial Melanoma Genes, Melanocyte Immortalization, and Melanoma Initiation....Pages 183-196
Genetic Progression From Melanocyte to Malignant Melanoma....Pages 197-209
The Multiple Roles of the Oncogenic Protein SKI in Human Malignant Melanoma....Pages 211-222
RB/E2F Regulation and Dual Activity in the Melanocytic System....Pages 223-245
Melanoma Development and Pigment Cell Transformation....Pages 247-263
The Biology and Genetics of Melanoma....Pages 265-290
The Biology of Xeroderma Pigmentosum....Pages 291-310
Divergent Pathways to Cutaneous Melanoma....Pages 311-327
Pigmentation, DNA Repair, and Candidate Genes....Pages 329-345
Low-Penetrance Genotypes, Pigmentation Phenotypes, and Melanoma Etiology....Pages 347-364
The Biology of Melanoma Progression....Pages 365-398
Front Matter....Pages 117-117
Optical Imaging Analysis of Atypical Nevi and Melanoma....Pages 399-408
Proteomics Analysis of Melanoma Cell Lines and Cultured Melanocytes....Pages 409-425
Front Matter....Pages 427-427
Paradigm of Metastasis for Malignant Melanoma....Pages 429-440
Repair of UV-Induced DNA Damage and Melanoma Risk....Pages 441-453
High-Risk Factors for Melanoma Metastasis....Pages 455-473
Role of Melanoma Inhibitory Activity in Early Development of Malignant Melanoma....Pages 475-487
Role and Regulation of PAR-1 in Melanoma Progression....Pages 489-502
Molecular Mechanisms of Melanoma Metastasis....Pages 503-511
Overview of Tumor Progression in Melanoma....Pages 513-532
The Plasticity of Melanoma Cells and Associated Clinical Implications....Pages 533-550
The Clinical Use of Molecular Markers as Predictors of Disease Outcome and Response to Therapy in Malignant Melanoma....Pages 551-576
The Role of DCT/TYRP2 in Resistance of Melanoma Cells to Drugs and Radiation....Pages 577-589
How Melanoma Cells Evade Chemotherapy....Pages 591-603
Apoptosis in Melanoma....Pages 605-617
Role of Melanoma-Associated Antigens....Pages 619-631
Host Responses to Melanoma....Pages 633-649
Future Perspectives....Pages 651-652
Back Matter....Pages 653-678