دانلود کتاب Medical bioinformatics and biochemistry (diabormatics)

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Medical Bioinformatics and Biochemistry (Diabormatics) Medical Bioinformatics and Biochemistry (Diabormatics) Contents Preface Chapter 1 Diabetes and Diabormatics: An Introduction Abstract Introduction 1.1. Diabetes: An Introduction 1.2. Role of Insulin and Glucagon in Regulating Blood Glucose Level 1.3. Medications for Diabetes Conclusion References Chapter 2 Combined Effect of Vitamin C and E Dose on Type 2 Diabetes Patients Abstract Introduction 2.1. Use of Vitamin C and E for Diabetes Treatment Conclusion References Chapter 3 In-Silico Structure Modelling and Docking Studies Using Dipeptidyl Peptidase-4 (DPP4) Inhibitors against Diabetes Type-2 Abstract 3. Introduction 3.1. Methodology 3.1.1. Sequences Retrieval and Alignment 3.1.2. Molecular Modelling of DPP4 3.1.3. Docking of DPP4 (NP_001926) with SKK 3.2. Results and Discussion 3.2.1. Building of Protein Model 3.2.2. Model Reputation 3.2.3. Model Validation Conclusion References Chapter 4 Homology Modelling and Structural Validation of Type 2 Diabetes Associated Transcription Factor 7-Like 2 (TCF7L2) Abstract Introduction 4.1. Methodology 4.1.1. Operating System 4.1.2. Sequence Retrieval, Alignment and Homology Modelling 4.1.3. Model Reputation 4.2. Results 4.2.1. Building of Protein Model 4.2.2. Model Reputation 4.2.3. Model Validation Conclusion References Chapter 5 Effect of Vitamin E and C Supplementation on Oxidative Stress in Diabetic Patients Abstract Introduction 5.1. Methodology 5.2. Results and Discussion Conclusion References Chapter 6 In Silico Structure Analysis of Type 2 Diabetes Associated Cysteine Protease Calpain-10 (CAPN10) Abstract Introduction 6.1. Methodology 6.1.1. Operating System 6.1.2. Retrieval of Sequences and Sequence Alignment 6.1.3. Molecular Modelling of Calpain10 6.2. Results and Discussion 6.2.1. Building of Protein Model 6.2.2. Model Reputation 6.2.3. Model Validation Conclusion References Chapter 7 To Evaluate the Role of Leptin in Diabetes for Male and Female Subjects Abstract Introduction 7.1. Methodology 7.2. Results Conclusion References Chapter 8 Study of Leptin and Adiponectin in Type 2 Diabetes Mellitus Abstract Introduction 8.1. Materials and Methods 8.2. Results Conclusion References Chapter 9 Study on Correlation of Inflammatory Markers on Type-II Diabetes Abstract Introduction 9.1. Uric Acid as an Inflammatory Marker in Diabetes Mellitus 9.2. CRP as an Inflammatory Marker in Diabetes Mellitus 9.3. Methods 9.3.1. Sample Size and Sampling method Conclusion References Chapter 10 Nano-Diabetology Abstract Introduction 10.1. Detection of Insulin and Blood Sugar 10.1.1. By Micro-Physiometer 10.1.2. By Implantable Sensor 10.2. Methodology 10.2.1. Conventional 10.2.2. Microsphere 10.2.3. Nano-Pump 10.2.4. Artificial Pancreas 10.3. Role of Nano Technology in Glucose Monitoring 10.3.1. Glucose Nanosensors 10.3.2. Layer-by-Layer (LBL) Technique 10.3.3. Carbon Nanotubes 10.3.4. Quantum Dots (QDs) 10.4. Development of Patient-Friendly Insulin Delivery Nanoparticle Formulations 10.4.1. Anti-Oxidative Role of Nanoparticles 10.5. Applications of Nanomedicine in Health Care and Disease Conclusion References Chapter 11 Effect of Ajowan Seed Powder on Oxidative Stress in Normal and Niddm Patients Abstract Introduction 11.1. Methodology 11.1.1. Statistical Analysis 11.2. Results Conclusion References About the Editors Index Blank Page