دانلود کتاب Modeling Fragile X Syndrome

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Front Matter....Pages i-xi
Front Matter....Pages 13-13
Introduction: Reminiscing on Models and Modeling....Pages 1-12
Probing Astrocyte Function in Fragile X Syndrome....Pages 15-31
Neural Stem Cells....Pages 33-40
Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System....Pages 41-59
The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome....Pages 61-80
Front Matter....Pages 81-81
Behavior in a Drosophila Model of Fragile X....Pages 83-117
Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome....Pages 119-156
Fragile X Mental Retardation Protein and Stem Cells....Pages 157-164
Manipulating the Fragile X Mental Retardation Proteins in the Frog....Pages 165-179
Exploring the Zebra Finch Taeniopygia guttata as a Novel Animal Model for the Speech–Language Deficit of Fragile X Syndrome....Pages 181-197
Front Matter....Pages 199-199
Neuroendocrine Alterations in the Fragile X Mouse....Pages 201-221
Taking STEPs Forward to Understand Fragile X Syndrome....Pages 223-241
Fmr-1 as an Offspring Genetic and a Maternal Environmental Factor in Neurodevelopmental Disease....Pages 243-253
Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome....Pages 255-269
Front Matter....Pages 271-271
Clinical Aspects of the Fragile X Syndrome....Pages 273-279
Fragile X Syndrome: A Psychiatric Perspective....Pages 281-295
Fragile X Syndrome and Targeted Treatment Trials....Pages 297-335
The Fragile X-Associated Tremor Ataxia Syndrome....Pages 337-357
Front Matter....Pages 359-359
Vignettes: Models in Absentia....Pages 361-383
Back Matter....Pages 385-390