دانلود کتاب Nano Comes to Life: How Nanotechnology Is Transforming Medicine and the Future of Biology

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Cover
Contents
Preface and Acknowledgments
Abbreviations
INTRODUCTION. Sciences Converge in Biology to Transform Health
Nanotechnology in Biology and Medicine
The Emergence of Quantitative Biology:
The New Physics of Life
The Transformation of Biology and Medicine
Transmaterial Futures
1. Embracing Biology’s Complexity, At Last
Hierarchical Universe, Hierarchical Life
Zooming In on Biological Complexity: Reducing Biology to Its Building Blocks
Zooming Out:
The Emergence of Biological Behavior out of Complexity
Using the
Tools of Nanotechnology to Investigate Biology
Observing the Function of Biomolecules: A Protein Performing Nano-Walks
Cellular Behavior
on Multiple Scales
How Do Whole Cells Respond to Forces and the Mechanical Environment?
Translating Mechanics into Biology
Bridging Scales
with Mechanical and Electrical Signals
Bioelectricity Programs Organs’ Activity
Hierarchical Biology, Hierarchical Brain . . . and Mind
By Embracing Biology’s Complexity, Science Is
Closing a Historical Loop of Thousands of Years
2. Learning by Making:
DNA and Protein Nanotechnology
The Birth of DNA Nanotechnology
Making Nanostructures with DNA
DNA Origami
DNA Nanorobots
Scaling Up DNA Nanotechnology
Protein Nanotechnology
Nanostructures
That Optimize Themselves through Biological Evolution
Building Biomimetic Materials and Devices
with Nanotechnology
Future Devices: Quantum Physics Meets Biology Meets Nanotechnology
3. Nano in Medicine
A Brief History of Drug Discovery and the
Arrival of Nanomedicine
Antibiotic Resistance
and Nanotechnology
Rational Drug Design Using Designer Proteins
DNA Nanorobots for Programmable Chemical Synthesis
Nanotechnology for Targeted Delivery of Drugs
Nanotechnology to Enhance Cancer Immunotherapy
Nanoparticles for Gene Editing and Gene Delivery
Controlled Release of Drugs and Molecules from Polymeric Materials
Controlled Release of Drugs from Skin Patches Using
Bioresponsive Materials
Implants for Improved Immunotherapies
Toward
the Super-Enhanced Immune System
4. Recreating Tissues and Organs
From the Discovery of Cells to Stem Cells
Early Tissue Engineering
Artificial Materials to Control the Fate of Stem Cells
Nanostructured Materials for Tissue Engineering
Engineering Organs
3-D
Bioprinting
Organs on a Chip
Using Biology, Physics, and Mathematics for Engineering
and Regenerating Tissues
The First Biohybrid, Transmaterial Robot
5.
Conclusions: Life Changes Everything
EPILOGUE. Biology Becomes Physics: Our Coming of Age as a Technological Species?
Scientists Strive for New Technological Cultures
Technology and Equality
Creating Visions of Positive Technological Futures
“Walk Forward in the Radiance of the Past\"
Notes
Index
Color Plates