دانلود کتاب Neopterin: Biochemistry - Methods - Clinical Application

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1 Pteridines\n1.1 Historical remarks\n1.2 Occurrence\n1.3 Biosynthesis\n1.4 Biochemical functions\nReferences\n2 Neopterin\n2.1 Chemical characteristics\n2.2 Catabolism\n2.3 Biochemical and physiological relevance\nReferences\n3 Measurement of Neopterin\n3.1 Historical remarks\n3.2 Measurement by reversed phase HPLC without pretreatment of samples\n3.3 Measurement of neopterin by reversed phase HPLC with on-line deproteinization\n3.4 Measurement of neopterin by immunoassays\nReferences\n4 Normal Ranges of Neopterin Concentrations in Various Body Fluids\n4.1 Normal ranges of neopterin concentrations in urine\n4.2 Normal ranges of neopterin concentrations in serum\n4.3 Normal ranges of neopterin concentrations in cerebrospinal fluid\n4.4 Normal ranges of neopterin concentrations in synovial fluid\n4.5 Normal ranges of neopterin concentrations in saliva\n4.6 Discussion\nReferences\n5 Biosynthesis of Pteridines and the Human Immune System\n5.1 Immunological activation and cytokines\n5.2 Cytokines and pteridine biosynthesis\n5.3 Inducers of pteridine synthesis in human cells\n5.4 Cell culture techniques\n5.5 Determination of pteridines in cell homogenates and supernatants\n5.6 Enzyme activities of pteridine synthesis in cell extracts\n5.7 Biological significance of cytokine-induced pteridine synthesis\nReferences\n6 Neopterin in Organ Transplantation\n6.1 Renal transplantation\n6.2 Transplantation of solid organs other than kidney\n6.3 Transplantation of bone marrow\nReferences\n7 Neopterin in Autoimmune Diseases and Related Inflammatory Disorders\n7.1 Neopterin in rheumatoid arthritis\n7.2 Neopterin in inflammatory bowel diseases\n7.3 Neopterin in autoimmune diabetes\n7.4 Neopterin in autoimmune diseases of the thyroid\n7.5 Neopterin in systemic lupus erythematosus\n7.6 Neopterin in multiple sclerosis\n7.7 Neopterin in sarcoidosis\n7.8 Neopterin in celiac disease\nReferences\n8 Neopterin in Malignant Diseases\n8.1 Hematological malignancies\n8.2 Gynecological malignancies\n8.3 Malignancies of the urogenital tract\n8.4 Lung cancer\n8.5 Gastrointestinal, pancreatic and hepatic cancer\n8.6 Breast cancer\n8.7 Cancers of the head and neck region\n8.8 Malignant melanoma\n8.9 Neopterin in malignant diseases - a summary\nReferences\n9 Neopterin in Infectious Diseases\n9.1 Infections by viruses\n9.2 Neopterin during infection by human immunodeficiency virus type 1 (HIV-1) and the acquired immunodeficiency syndrome (AIDS)\n9.3 Infections by intracellular protozoa\n9.4 Infections by bacteria\n9.5 Neopterin during sepsis and trauma\nReferences\n10 Monitoring of Immunostimulatory Therapy\nReferences\n11 Neopterin in Transfusion Medicine\nReferences\nAppendix\nReferences\nSubject Index