دانلود کتاب Neuropsychological Tools for Dementia: Differential Diagnosis and Treatment

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Neuropsychological Tools for Dementia\nCopyright\nContents\nPreface\n1 Introduction: neuropsychology and the assessment of patients with dementia\n General summary\n 1.1 Some epidemiological background information\n 1.2 Dementia is a syndromic and not a causal diagnosis\n 1.3 International classification of disease diagnosis codes for dementia—still more than noticing abnormal biomarkers\n 1.3.1 Summary\n 1.4 Neuropsychological testing in patients suspected for dementia\n 1.4.1 Screening instruments: the mini mental status examination\n 1.4.2 Screening with the mini mental status examination for predicting instrumental activities in daily living independence\n 1.4.3 Other screening instruments\n 1.4.4 Summary of screening for dementia\n 1.5 Assessing patients for differential diagnosis\n 1.5.1 Some general remarks on the meaning of the medical history for the neuropsychological assessment\n 1.5.2 The CERAD-NAB as core assessment battery\n 1.5.3 The CERAD-NAB for differential diagnosis\n 1.5.4 Additional tests and the assessment of behavioral disorders, depressive mood, and instrumental activities in daily living\n 1.5.5 Summary\n 1.5.6 Assessing middle-aged and/or high performing patients\n 1.6 Structured and efficient testing presupposes a structured and efficient anamnesis\n 1.7 Summary: Prospect of neuropsychological testing of dementia\n References\n2 Alzheimer’s disease: neuropathology, neuropsychological differential diagnosis, and treatment\n 2.1 General summary\n 2.2 Alzheimer’s disease—clinical signs and assessment\n 2.3 Some remarks on the neuropathology of Alzheimer’s disease and its biomarkers\n 2.4 Alzheimer’s disease—specificity and sensitivity of neuropsychological testing in Alzheimer’s disease\n 2.4.1 Memory impairments and global memory testing\n 2.5 Specificity and sensitivity of other memory tests for detecting an amnestic syndrome of the hippocampal type (i.e., Alz...\n 2.6 Two case descriptions\n 2.7 Summary of neuropsychological testing in patients suspected for Alzheimer’s disease\n 2.8 Prediction of conversion to Alzheimer’s disease by neuropsychological tests\n 2.8.1 Prediction using the WMS logical memory test and the ADNI neuropsychological mild cognitive impairment criteria\n 2.8.2 Prediction using the CERAD-NAB or standard neuropsychological tests\n 2.8.3 How early can cognitive impairments be measured in patients converting to dementia?\n 2.8.4 Prediction of conversion with the help of specific memory processes\n 2.8.5 Problems for predicting conversion to dementia using neuropsychological test results\n 2.8.6 A note on prediction from mild cognitive impairment to dementia based on biomarkers\n 2.8.7 Summary\n 2.9 Is a treatment of Alzheimer’s disease and mild cognitive impairment effective and therefore necessary?\n 2.9.1 Lifestyle and pharmacological interventions in mild cognitive impairment patients and the conversion to Alzheimer’s d...\n 2.9.2 Treatment of Alzheimer’s disease patients with neuropsychological interventions\n 2.9.3 Summary\n 2.10 Alzheimer’s disease and neuropsychological models of false positives in recognition\n References\n3 The alphasynucleinopathies: Parkinson’s disease, Lewy body dementia, and multisystem atrophy\n 3.1 General summary\n 3.2 Parkinson’s disease\n 3.2.1 Clinical symptoms\n 3.2.2 Neuropathology of the alphasynucleinopathies and the prodromal signs of Parkinson’s disease\n 3.2.2.1 Summary\n 3.2.3 Neuropsychology of Parkinson’s disease without dementia\n 3.2.4 Cognitive impairment and the functional independence of the patients\n 3.2.5 Functional treatment of nondemented Parkinson’s disease patients\n 3.2.6 A case example\n 3.2.7 Summary\n 3.3 Parkinson’s disease dementia\n 3.3.1 Criteria for Parkinson’s disease with dementia, risk factors for conversion, and meaning of cognitive impairment for ...\n 3.3.2 Prediction of conversation to Parkinson’s disease with dementia by neuropsychological tests\n 3.3.3 Treatment of Parkinson’s disease with dementia\n 3.3.4 Summary\n 3.4 Lewy body dementia\n 3.4.1 Clinical criteria and the relation to Parkinson’s disease dementia\n 3.4.2 Attention testing and cognitive fluctuations in Lewy body disease (and Parkinson’s disease with dementia)\n 3.4.3 Visual deficits and visual hallucinations in Lewy body disease (and Parkinson’s disease with dementia)\n 3.4.4 Treatment of Lewy body disease (and Parkinson’s disease with dementia)\n 3.4.5 A case example\n 3.4.6 Summary\n 3.5 Multisystem atrophy\n 3.5.1 Clinical symptoms and neuropathological findings\n 3.5.2 Neuropsychological and clinical findings in multiple system atrophy patients\n 3.5.3 Summary\n 3.6 Visuoperceptive, visuoconstructive impairments, and visual hallucinations in typical and atypical Parkinson’s syndromes\n References\n4 Atypical Parkinson’s diseases: progressive supranuclear palsy and corticobasal degeneration\n 4.1 General summary\n 4.2 Progressive supranuclear palsy\n 4.2.1 Introduction, definition, and epidemiology\n 4.2.2 Neurological aspects of progressive supranuclear palsy\n 4.2.2.1 Gait and postural instability in progressive supranuclear palsy\n 4.2.2.2 Examination of the eyes and of eye movements relevant for progressive supranuclear palsy and corticobasal degenerat...\n 4.2.3 Neuropsychological test impairments in progressive supranuclear palsy\n 4.2.3.1 Tests and test results for bimanual coordination, apraxia, and disinhibition\n 4.2.3.2 Neuroradiological signs for progressive supranuclear palsy\n 4.2.3.3 Case presentation\n 4.3 Corticobasal degeneration or corticobasal syndrome\n 4.3.1 Diagnostic criteria and terminology\n 4.3.2 Motor impairment and apraxia in corticobasal degeneration or corticobasal syndrome\n 4.3.3 Disorders in eye movements and visuoperception in corticobasal degeneration or corticobasal syndrome\n 4.3.4 Calculation impairment and memory impairment in corticobasal degeneration or corticobasal syndrome\n 4.3.5 Alien hand sign in corticobasal degeneration or corticobasal syndrome\n 4.3.6 Neuroradiological signs for corticobasal degeneration or corticobasal syndrome\n 4.4 A simplified guide for differentiating between atypical Parkinson’s diseases\n 4.4.1 Summary: a neuropsychological-clinical guide for the differential diagnosis\n 4.4.2 Some remarks on pathogenesis of progressive supranuclear palsy and corticobasal degeneration\n 4.5 Treatment\n 4.6 Summary\n 4.7 How can disinhibition in progressive supranuclear palsy and corticobasal syndrome be explained in neuropsychological terms?\n References\n5 Primary progressive aphasias\n 5.1 General summary\n 5.2 Introduction to the clinical syndromes\n 5.3 Nonfluent primary progressive aphasia\n 5.3.1 Clinical core features\n 5.3.2 Characteristics of speech in nonfluent primary progressive aphasia\n 5.3.3 Language comprehension\n 5.3.4 Other cognitive features of nonfluent primary progressive aphasia\n 5.3.5 Case presentation\n 5.4 Semantic dementia\n 5.4.1 Clinical core features\n 5.4.2 Cognitive impairments in semantic dementia\n 5.4.3 Phonological working memory impairment in semantic dementia\n 5.4.4 Case presentation\n 5.5 Logopenic primary progressive aphasia\n 5.5.1 Clinical core features\n 5.5.2 Verbal working memory deficits in logopenic primary progressive aphasia\n 5.5.3 Episodic memory deficits in logopenic primary progressive aphasia\n 5.5.4 Case presentation\n 5.6 Dyslexia and the primary progressive aphasias\n 5.7 A diagnostical schema to distinguish the three subtypes of primary progressive aphasias\n 5.8 Treating the language variants of dementia\n 5.9 Summary\n 5.10 Cerebral atrophy and neuropathology\n 5.11 The language variants of dementia and the acquired aphasia\n References\n6 Behavioral variant of frontotemporal dementia\n 6.1 General summary\n 6.2 Clinical symptoms of behavioral frontotemporal dementia\n 6.3 Neuropathological subtypes of behavioral frontal temporal dementia and biomarker results\n 6.4 Neuropsychological impairments in behavioral frontal temporal dementia and their assessment\n 6.5 A case report\n 6.6 Treatment of behavioral frontal temporal dementia\n 6.7 Summary\n 6.8 Behavioral frontal temporal dementia and neurodegeneration of von Economo and fork cells in the right anterior insular ...\n References\n7 Normal pressure hydrocephalus\n 7.1 General summary\n 7.2 Clinical, neuroradiological features of idiopathic normal pressure hydrocephalus, and its diagnosis\n 7.3 Neurophysiology and neuroanatomy of idiopathic normal pressure hydrocephalus\n 7.4 Treatment of normal pressure hydrocephalus\n 7.5 Neuropsychology of normal pressure hydrocephalus\n 7.5.1 Are there characteristic cognitive features of idiopathic normal pressure hydrocephalus?\n 7.5.2 Does neuropsychological examination predict the success of shunt surgery?\n 7.5.3 Are there cognitive functions that respond to the spinal tap test?\n 7.5.4 A case example with secondary normal pressure hydrocephalus\n 7.6 Summary\n 7.7 The mesial frontal system and the functional impairment of idiopathic normal pressure hydrocephalus\n References\n8 A short guideline for the neuropsychological differential diagnosis of the dementias\n9 Overview treatment options\nIndex