دانلود کتاب NUTRITIONAL AND INTEGRATIVE STRATEGIES IN CARDIOVASCULAR MEDICINE.

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Cover Half Title Title Page Copyright Page Table of Contents Introduction Editors Contributors Chapter 1 Nutrition, the Mediterranean Diet and Selected Supplements for the Prevention and Treatment of Coronary Heart Disease Introduction Revolutionizing the Treatment of Coronary Heart Disease and Interrupting the Finite Pathways Atherosclerosis, Endothelial Dysfunction and Arterial Stiffness Nutrition and CHD Specific Diets and Coronary Heart Disease Mediterranean Diet (TMD: Traditional Mediterranean Diet) (PREDIMED Diet) Dietary Approaches to Stop Hypertension (DASH) Diets (DASH 1 and 2) Dietary Fats Omega 3 Fatty Acids (PUFA) Monounsaturated Fats Saturated Fatty Acids Conclusions and Summary on SFA [14,28,31–56] Trans Fatty Acids Coconut Oil Milk, Milk Products and Peptides Whey Protein Eggs Refined Carbohydrates, Sugars and Sugar Substitutes Advanced Glycation End Products (AGEs) Protein Vegetarian Diets and Plant-Based Nutrition Animal Protein Diets Soy Protein Fish Dietary Acid Load and Protein Specific Dietary and Nutritional Components and Caloric Restriction Caffeine Caloric Restriction Alcohol Gluten Nuts Dietary Sodium, Potassium and Magnesium Summary and Conclusions References Chapter 2 Coronary Artery Disease: The Impact of the Mediterranean Cuisine, Targeted Nutritional Supplements and Their Relationship to Autophagy/mTOR Takeaways and Key Concepts What Is So Powerful about Polyphenols? Cocoa and Dark Chocolate Extra Virgin Olive Oil – The King of Polyphenols How Do You Know Your Olive Is Premium? How to Select Your Olive Oil The Nutritional Benefits of Artichokes Artichoke Health Benefits Lycopene – The Carotenoid of Tomatoes Tomato Nutrition Nattokinase and Lumbrokinase Astaxanthin – My Discovery in Japan Omega-3s NMN/Autography/mTOR The Body Heals Itself mTOR References Chapter 3 Naturopathic Medicine and the Prevention and Treatment of Cardiovascular Disease Introduction Vegetarian, Paleolithic, and Mediterranean Diets – Food as Medicine The Standard Western Diet and Refined Sugar Wheat (gluten), Blood Sugar, and Inflammation Know Thy Food Source Understanding Atherosclerosis The Vascular Lining– A Key Target for Nutritional Therapies The Role of Nutrition and Endothelial Function Berberine Garlic Pantethine Bergamot The Naturopathic Approach to Treating Hypertension Diet, Lifestyle, and Hypertension Special Foods to Lower Blood Pressure The DASH Diet Fluids, Salt, and Hypertension Exercise and Hypertension Stress, Breathing, and Hypertension Targeted Nutritional Supplements, Botanical Medicines, and Acupuncture and Hypertension Fasting and Hypertension Grounding and Hypertension Monitor Your Blood Pressure Concise Recommendations for High Blood Pressure The Importance of Detoxification in Supporting the Cardiovascular System The Effects of Environmental Toxins on Blood Pressure and the Cardiovascular System Introduction Reducing Toxic Exposure with Simple and Easy Interventions Sauna Therapy High-Fiber, Phytonutrient-Rich, Organic Fruits and Vegetables Liver and Gastrointestinal Supportive Foods and Botanical Medicines Skin Brushing Contrast Hydrotherapy Therapeutic Fasting Electromagnetic Radiation (EMR) Summary Conclusion References Chapter 4 Marine-Derived Omega-3 Fatty Acids and Cardiovascular Disease Omega-3 Fatty Acids Sources of Marine Omega-3 Ingredients Delivery Forms for Supplementation The Epidemiology of Omega-3 Fatty Acids and CVD Omega-3 Index and CVD Risk CVD Intervention Studies Using Omega-3 Fatty Acids REDUCE-IT (2018) VITAL (2018) ASCEND (2018) STRENGTH (2020) Cardiometabolic Mechanisms and Biomarkers Related to EPA and/or DHA LDL, HDL and Non-HDL Cholesterol Inflammatory Biomarkers and Specialized Pro-Resolving Mediators Bioavailability of n-3 Supplements Ethyl Esters vs Triglycerides Krill Oil vs Fish Oil Astaxanthin from Krill Additional Considerations on Marine Omega-3 Sourcing Allergies to Fish and Shellfish Related to Omega-3 Products Quality Control Issues of Fish Oil and Related Products Conclusion and Recommendation References Chapter 5 Nutrition and Nutritional Supplements in the Management of Dyslipidemia and Dyslipidemia-Induced Cardiovascular Disease Introduction Pathophysiology Treatment Overview Nutrition Framingham Heart Study and Seven Countries Study Pritikin Diet Ornish Diet Therapeutic Lifestyle Changes (TLC) Diet OmniHeart Trial Portfolio Diet Mediterranean Diets Lyon Diet Heart Study Indian Heart Study Nutrigenomics The FUNGENUT Study The GEMINAL Study The PREDIMED Study Nutritional Conclusions and Recommendations Specific Foods, Nutrients, and Dietary Supplements Omega-3 Fatty Acids Flax Monounsaturated Fats (MUFA) Garlic Green Tea Orange Juice Pomegranate Juice and Seeds Sesame Soy Nutrients and Dietary Supplements Citrus Bergamot Curcumin Guggulipids Lycopene Niacin (Vitamin B3) Pantethine Plant Sterols (Phytosterols) Policosanol Tocotrienols Red Yeast Rice Resveratrol Vitamin C Berberine Combination Therapies Future Perspectives Summary and Conclusions References Chapter 6 The Role of Nitric Oxide Supplements and Foods in Cardiovascular Disease Introduction Loss of Nitric Oxide Production Is Responsible for CVD Diet and Lifestyle Habits That Disrupt NO Production Standard American Diet Use of Mouthwash and Antibiotics Antacids Inhibit NO Production Certain Food Patterns Increase NO Production Resveratrol Curcumin Nitric Oxide Supplements Conclusions References Chapter 7 The Treatment of Hypertension with Nutrition, Nutritional Supplements, Lifestyle and Pharmacologic Therapies Introduction Epidemiology and Pathophysiology The Three Finite Vascular Responses and Cardiovascular Disease (Figures 7.1 and 7.2) Oxidative Stress, Inflammation and Vascular Immune Dysfunction The Balance of Hypertension Treatment of Hypertension with Nutrition and Nutritional Supplements Sodium (Na[sup(+)]) Potassium Magnesium (Mg[sup(++)]) Calcium (Ca[sup(++)]) Zinc (Zn[sup(++)]) Protein L-Arginine Taurine Omega-3 Fats and Selected Omega-6 Fats Monounsaturated Fatty Acids (MUFA): Olive Oil, Mediterranean Diet, Omega-9 Fats, Oleic Acid and Olive Leaf Extract Vitamin C Vitamin E Vitamin D Vitamin B6 (Pyridoxine) Flavonoids: Resveratrol and Pomegranate Lycopene Coenzyme Q10 (Ubiquinone) Alpha Lipoic Acid Pycnogenol Garlic Seaweed Cocoa: Dark Chocolate Melatonin Grape Seed Extract Dietary Nitrates and Nitrites: Beetroot Juice and Extract Teas L-Carnitine and Acetyl–L-Carnitine Fiber Sesame Hesperidin N-Acetylcysteine (NAC) Hawthorn Quercetin Probiotics Drug Therapy for Hypertension Clinical Considerations Summary References Chapter 8 Metabolic Cardiology: Management of Congestive Heart Failure Takeaways and Key Concepts The Secrets of the Cell Energy Starvation in the Failing Heart Energy Nutrients for Congestive Heart Failure D-Ribose (Ribose) Coenzyme Q10 and the Heart CoQ10– Inflammatory Coronary Heart Disease/Diabetes Coenzyme Q10 Varietals– Ubiquinone, Ubiquinol and MitoQ Levocarnitine (L-Carnitine or Carnitine) Magnesium– Switching on the Energy Enzymes Taurine Summary Conclusion References Chapter 9 Cardiovascular Disease in Women Case: 60-Year-Old Female with Nausea and Vomiting Sex Differences Gender Differences Racial Disparities Defining the Problem in Women Diastolic Dysfunction Hypertension Mitral Valve Prolapse Peripheral Artery Disease Summary References Chapter 10 Hormones and Cardiovascular Disease CVD in Women Estradiol and CVD Low Estradiol and CVD Hormones and Metabolism Effects of Menopausal Hormone Therapy How Does Hormone Therapy Affect Risk of CVD? Critical Window or “Timing” Hypothesis Is Hormone Therapy Good for Every Woman? Methods of Hormone Therapy Summary: Women and CVD CVD in Men Low Testosterone and CVD What Causes Low T and How Prevalent Is It? What About Treating Low T with Testosterone Replacement Therapy (TRT)? Role of DHEA Is TRT Good for Every Man with Low T? How to Treat Methods of TRT Non-Pharmaceutical Approaches Exercise Natural Supplements Summary: Men and CVD Conclusion References Chapter 11 The Heartbreak of Wheat-Related Disorders: Wheat, Gluten and Cardiovascular Disease Frequency of a Wheat-Related Disorder The Immune Response to Wheat Causes of Wheats’ Immunogenicity Abbreviations References Chapter 12 The Role of the Gut Microbiome in Cardiovascular Disease Pathophysiology of Cardiovascular Disease as It Relates to the Gut Microbiome Metabolic Endotoxemia and Cardiovascular Disease Hypertension and the Gut Microbiome Periodontal Disease and Cardiovascular Disease Specific Microbial Species and Microbiota Composition Associated with Cardiovascular Health Risks The Effects of Certain Dietary Components on the Gut Microbiota and Cardiovascular Disease Clinical Presentation of Cardiovascular Disease Driven by Gut Microbiology Prevention and Treatment Strategies Summary Future Challenges References Chapter 13 Environmental Toxins and Cardiovascular Disease Introduction Lead Sources Primary Measure Primary Intervention Air Pollution Sources Primary Measure Primary Intervention Persistent Organic Pollutants (POPs) Sources Primary Measure Primary Intervention Bisphenols Sources Primary Measure Primary Intervention Systemic Approaches GGTP (Gamma Glutamyl Transferase) Sauna Conclusion References Chapter 14 Dental Disease, Inflammation, Cardiovascular Disease, Nutrition and Nutritional Supplements Introduction Periodontal Disease, Caries, Periapical Infections, Inflammatory Infiltrates and the Inflammatory Cascade What Is Periodontal Disease and What Causes It? The Guilty Bugs: Oral Biofilm in Periodontal Disease, Caries and Periapical Disease – Effects on Cardiovascular Disease What We Know about the Systemic Connection The Dynamic Duo: How Does Blood Glucose Control and Diabetes Impact Periodontal and Cardiovascular Diseases Cardiovascular Disease (CVD) Periodontal Disease and Atherosclerosis as an Inflammatory Process Diagnosing Periodontal Disease Periodontal Disease: Treatment and Maintenance Host Modulation How Can We Better Manage Oral Biofilms? Host Modulation Using Nutrition Biofilm Elimination over the Long Term Collaboration between the Physician and Dentist Collaborative Inflammation and Biofilm Treatment: Dentistry and Medicine References Chapter 15 COVID-19: An Evidence-Based Integrative Approach to Disease Management What Is COVID-19 (Virology)? What Are COVID-19 Variants? Pathophysiology of COVID-19 Why Is the Endothelium a Prime Target Organ in COVID-19? How Is COVID-19 Transmitted? How Is Testing Impacted by Viral Replication and Immune Responses? Incubation Periods and Impact on PCR Testing Strategies Period of Infectivity Serology and B-Cell Immunity T-Cell Responses to COVID-19 Antigen Tests and Limitations Tests to Define Prognosis and Status PULS Cardiac Test D-Dimer Other Tests Useful in COVID-19 How to Apply an Integrative Approach to Preventing and Caring for COVID-19 Patients Strategies to Boost Immunity Summary References Chapter 16 Lymphstasis, Inflammation and Atherogenesis – Connecting the Dots Inflammation and Covid Lymph and Chronic Inflammation Lifestyle Plus Epigenetics References Chapter 17 Vitamin G. Grounding as Energetic Nutrition and Its Role in Oxidative Defense and Cardiovascular Disease Blood Pressure Considerations Grounding and the Immune System Grounding and Energy Summary References Chapter 18 The Role of Botanicals in Cardiovascular Health Introduction Cardiovascular Tonics Khella Dried Ripe Fruit and Seed (Ammi visnaga L.) Arjuna Tree Bark (Terminaliaarjuna Roxb. ex DC.) Hawthorn Berry, Flower, and Leaf (Crataegus spp.) Garlic (Allium sativum L.) Grape Seed (Vitis vinifera L.) Anti-Hypertensives Hibiscus Calyces (Hibiscus sabdariffa L.) Beetroot (Beta vulgaris L.) Nervine Relaxants Lemon Balm Leaf (Melissa Officinalis L.) Motherwort Herb (Leonurus cardiaca L.) Vascular Tonics Horse Chestnut (Aesculus hippocastanum L.) Pycnogenol Quality of Botanical Products Summary References Chapter 19 Depression, Anxiety, Stress, and Spirituality in Cardiovascular Disease Depression Anxiety Overlap between Anxiety and Depression Defining Anxiety Stress Stressors Pathophysiology Biological Mechanisms Inflammation Platelet Activation Autonomic Dysfunction HPA Axis Dysfunction Endothelial Dysfunction Cardiovascular Reactivity Acute Emotional Effects Behavioral Mechanisms Prevention and Screening Conventional Treatment Integrative Treatment Diet Gut Health Nutritional Supplements Herbal Therapies Herbal Anxiolytics Herbal Adaptogens Light Therapy Mind-Body Techniques Heart Rate Variability Breathing Meditation Lifestyle Exercise Yoga Social Support and Compliance Spirituality Summary Challenges Take Away Messages References Index