دانلود کتاب Orexin and Sleep: Molecular, Functional and Clinical Aspects

فهرست مطالب :

Front Matter....Pages i-xiv
History of Orexin Research....Pages 1-25
The Hypocretin Story....Pages 27-35
Input and Output Systems of Orexin Neurons....Pages 37-52
Physiological Roles of Orexin Receptors on Sleep/Wakefulness Regulation....Pages 53-65
Orexin Receptor Functions in the Ascending Arousal System....Pages 67-80
Elucidation of Neuronal Circuitry Involved in the Regulation of Sleep/Wakefulness Using Optogenetics....Pages 81-92
Optogenetic Dissection of Sleep-Wake Circuits in the Brain....Pages 93-105
Modulation of Thalamocortical Pathways by Orexins....Pages 107-135
Orexin, Alcohol and Sleep Homeostasis....Pages 137-164
Orexin Induced Modulation of REM Sleep and Its Loss Associated Patho-Physiological Changes Are Mediated Through Locus Coeruleus....Pages 165-180
Role of Orexin on Sleep: Interactions with Other Neurotransmitter Systems....Pages 181-202
Animal Models of Narcolepsy....Pages 203-212
Symptomatic Narcolepsy or Hypersomnia, with and Without Orexin (Hypocretin) Deficiency....Pages 213-258
Narcolepsy and Idiopathic Hypersomnia....Pages 259-287
Hypocretin/Orexin Pathology in Human Narcolepsy with and Without Cataplexy....Pages 289-298
Orexin and Circadian Influences in Sleep and Psychiatric Disorders: A Review of Experimental and Computational Modelling Studies....Pages 299-322
A New Class of Hypnotic Compounds for the Treatment of Insomnia: The Dual Orexin Receptor Antagonists....Pages 323-338
Pathway and Effect of Intranasal Orexin....Pages 339-351
Hypocretin (Orexin) Cell Transplantation as a New Therapeutic Approach in Narcolepsy....Pages 353-362
Orexin and Metabolism....Pages 363-380
Orexin Regulates Glucose Homeodynamics with Daily Rhythm....Pages 381-394
Orexinergic Tone in Cardiorespiratory Regulation....Pages 395-410