دانلود کتاب Phytoecdysteroids: Properties, Biological Activity and Applications

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Preface
Contents
About the Authors
1 Phytoecdysteroids
1.1 Characteristics of Phytoecdysteroids
1.2 Biosynthesis of Phytoecdysteroids
1.3 Distribution of Ecdysteroids in the Plant World
1.4 Structure and Sources of Phytoecdysteroids
References
2 Spectral Methods for Studying Phytoecdysteroids
2.1 Mass Spectra of Ecdysteroids
2.2 Proton Magnetic Resonance Spectroscopy
2.3 Carbon Magnetic Resonance Spectroscopy
References
3 Chemical Transformations of Phytoecdysteroids
3.1 Transformations in Ring A
3.2 Transformations in Ring B
3.3 Transformations in Rings C and D
3.4 Side-Chain Transformations
References
4 Some Aspects of Isolation and Chemical Transformation of Phytoecdysteroids
4.1 General Information
4.2 Phytoecdysteroids of the Plant Ajuga Turkestanica (Rgl.) Brig
4.3 Phytoecdysteroids of the Plant Rhaponticum Carthamoides (Wild) Iljin
4.3.1 The Structure of Carthamasterone A
4.3.2 The Structure of Carthamasterone B
4.3.3 The Structure of 24 (28)-Dehydromakisterone A
4.3.4 The Structure of 22-O-Benzoate-Polypodine B
4.3.5 α-Ecdysone Identification
4.4 Phytoecdysteroids of the Plant Rhaponticum Integrifolium C. Winkl
4.5 Phytoecdysteroids Silene Brahuica Boiss
4.5.1 Identification of Ecdysterone and Sileneoside C
4.5.2 The Structure of 25-O-Acetate-Integristerone A
4.5.3 The Structure of Sileneoside H
4.6 Phytoecdysteroids Silene Tomentella Schischk
4.6.1 The Structure of Tomentesterone A
4.6.2 The Structure of Tomentesterone B
4.6.3 Identification of Viticosterone E, 2-Deoxy-Α-Ecdysone, Polypodine B, Ecdysterone, Integristerone A, Sileneoside D
4.7 Phytoecdysteroids of Plants of the Genus Silene Wallichiana Klotzsch
References
5 Reactions of Phytoecdisteroids and Their Chemical Modification
5.1 Synthesis of Thiocarbamate Derivatives of 2-Deoxyecdysterone
5.2 Synthesis of Derivatives of Cyasterone Thiocarbamates
5.3 Synthesis of Silenosterone
5.4 Synthesis of 22-O-Benzoate-20-Hydroxyecdysone
5.4.1 New Acetonide Derivatives of 20-Hydroxyecdysone
5.4.2 Synthesis of 2,3-O-Di-(Ethyl Carbonate) -20,22-O-Carbonate-20-Hydroxyecdysone
5.4.3 Synthesis of 20-Hydroxyecdysone Hexanesulfonic Acid Derivatives
5.4.4 Synthesis of O-Chlorobenzoyl Derivatives of 20-Hydroxyecdysone
5.4.5 Synthesis of O-Methoxybenzoyl Derivatives of 20-Hydroxyecdysone
5.4.6 Synthesis of O-Methoxybenzoyl-Substituted Turkesterone
5.4.7 Synthesis of 20-Hydroxyecdysone Picolinate Derivatives
5.4.8 Synthesis of 6-Chloronicotinate Derivatives of 20-Hydroxyecdysone
5.4.9 Synthesis of 20-Hydroxyecdysone Hydrazones
5.5 Alkaline Hydrolysis of Ecdysteroids
5.5.1 Alkaline Hydrolysis of Tomentesterone A
5.5.2 Alkaline Hydrolysis of Tomentesterone B
5.5.3 Alkaline Hydrolysis of 3-O-Benzoate-2-Deoxyecdysterone
5.5.4 Alkaline Hydrolysis of 22-O-Benzoate-Polypodine B
5.6 Acylation Reactions
5.6.1 Obtaining 3,22-O-Diacetate-Tomentesterone B
5.6.2 Obtaining of Tomentesterone A from 3,22-O-Diacetate-Tomentesterone B
5.6.3 Obtaining 2,3-O-Diacetate-22-O-Benzoyl-Polypodine B
5.7 Oxidation Reactions
5.7.1 Oxidation of 3-Keto-22-O-Acetate-2-Deoxy-Α-Ecdysone
5.7.2 Oxidation of 3-Keto-2-Deoxy-Α-Ecdysone
References
6 Biological Activities of Phytoecdisteroids
6.1 Hormonal and Growth-Stimulating Activity of Phytoecdysteroids
6.2 Pharmacological Activity of Phytoecdysteroids
References
7 Technologies for Producing Drugs and Biologically Active Additives Based on Ecdysteroids from Plants Rhaponticum Carthamoides, Silene Praemixta, and Ajuga Turkestanica
7.1 Technology Overview
7.2 Methods for the Isolation of Ecdysteroids
7.3 The Technology to Produce Ecdysterone from Roots with Rhizomes and Seeds of Rhaponticum Carthamoides
7.3.1 Characteristics of Raw Materials
7.3.2 Selection of Selective Extractant
7.3.3 Optimization of the Ecdysterone Extraction Process
7.4 Supplements for Household Chemicals Based on Lipid Waste Ecdysteroid Production
7.5 Isolation of Ecdysterone from Rhaponticum Carthamoides Seeds
7.6 The Technological Process of Ecdysterone Production from Inflorescences of Rhaponticum Integrifolium
7.7 Technological Process for the Production of Ecdysterone from Silene Praemixta M. Pop
7.8 Ajuga Turkestanica Aerial Processing Technology
7.8.1 The Technological Process for Producing Ecdysterone from Aerial Part Ajuga Turkestanica
7.8.2 The Technological Process for Producing Turkesterone from Aerial Part A. Turkestanica
7.8.3 Technology for Isolating Ajustan Substance from A. Turkestanica
7.8.4 The Technological Process for Producing Jistenin’s BAA from Aerial Part Ajuga Turkestanica
7.8.5 Technological Process for Producing Eksumid from Aerial Part Ajuga Turkestanica
References