دانلود کتاب Radiotherapy in Skin Cancer: A Practical Guide on Indications and Techniques

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Foreword
Preface
Contents
Editors and Contributors
About the Editors
Contributors
Part I: General Principles of Skin Radiotherapy
Chapter 1: Classification and Pathology of Common Cutaneous Malignancies
Introduction
Basal Cell Carcinoma
Histological Types
Low-Risk of Recurrence BCC
High-Risk of Recurrence BCC
Immunohistochemical Profile
Predictive Parameters and Prognosis
Cutaneous Squamous Cell Carcinoma
Risk Factors
Clinical Presentation
Histopathology and Histological Types
Immunohistochemical Profile
Predictive Parameters and Prognosis
Pathological Staging
Merkel Cell Carcinoma
Clinical Presentation
Histogenesis and Types
Histopathology
Immunohistochemical Profile
Predictive Parameters and Pathological Staging
Cutaneous Melanoma
Histological Types
Superficial Spreading Melanoma
Lentigo Maligna Melanoma
Nodular Melanoma
Acral Melanoma
Desmoplastic Melanoma
Immunohistochemical Profile
Predictive Parameters and Pathological Staging
Other Cutaneous Malignancies
Malignant Appendageal Tumor
Primary Cutaneous Lymphoma
Malignant Cutaneous Soft Tissue Tumor
References
Chapter 2: Basic Medical Physics
Superficial and Orthovoltage Radiotherapy (SXRT/DXRT)
Interaction of Low-Energy Photons with Matter: Photoelectric Effect
Energy and Atomic Number Dependence
Half-Value Layer
Percent Depth Doses
Effect of f-Factor in Superficial/Orthovoltage Treatments
Field Defining Cutouts and Internal Shields
Surface Heterogeneities: Stand-Off and Stand-In Corrections
Superficial/Orthovoltage Dose Calculation
Electron Beam RT
Electron Percent Depth Dose
Bolus
Electron Field Shaping
Electron Backscatter
Effect of Treatment Field Size
Isodose Profile Characteristics
Effect of Inhomogeneities
Effects of Beam Obliquity
Electron Dose Calculation
References
Chapter 3: Skin Radiotherapy Treatment Planning
General Considerations
Patient Selection
Tumor Factors
Steps Involved in Treatment Planning
Target Volume Definition
Gross Tumor Volume (GTV)
Clinical Target Volume (CTV)
Planning Target Volume (PTV)
Selection of RT Technique
Superficial or Orthovoltage Irradiation
Electron Beam Therapy
Planning Considerations for Electron Beam Therapy
Treatment Scheme
References
Chapter 4: Dose Fractionation in Skin Radiotherapy
Standard Once-a-Day Fractionations
Nonstandard Fractionations
One Single Dose
Non-daily Fractions
Specific Clinical Considerations in Radiotherapy of Skin Cancers
The Issue of Relative Biological Effectiveness (RBE) and f-Factor of Orthovoltage X-rays Versus Electrons or Megavoltage X-rays
f-Factor for Bone and Cartilage for Superficial or Orthovoltage X-rays
Adjuvant Dose Fractionation
Melanomas
References
Part II: Site-Specific Indications and Techniques
Chapter 5: Nasal Skin
Indications for Radiotherapy
Treatment Approach
Treatment Planning
Target Volume
Dose
Treatment-related Side Effects
Outcomes
References
Chapter 6: Scalp
Introduction
Indications for Radiotherapy
Adjuvant
Definitive
Palliative
Treatment Approach
Treatment Planning
Target Volume
Local Treatment
Palliative
Dose
Adjuvant
Definitive
Palliative
Treatment-Related Side Effects
Outcomes
Follow-Up
References
Chapter 7: Eyelid
Anatomy and Histology of the Eyelid as Relevant to RT
Indications for Radiotherapy and Treatment Approach
Treatment Planning
The Eyelid as an RT Organ at Risk (OAR)
Dose
Treatment-Related Side Effects
Acute Effects
Late Effects
References
Chapter 8: Lip
Indications for Radiotherapy
Treatment Approach
Treatment Planning
Target Volume
Treatment Set-Up and Field Arrangement
Elective Nodal Irradiation
Dose
Treatment-Related Side Effects
Palliative Radiotherapy
Outcomes
References
Chapter 9: Ear
Introduction
Indications for Radiotherapy
Treatment Approach
Treatment Planning
Dose
Treatment-Related Side Effects and Management
Outcomes
References
Chapter 10: Extremities
Indications for Radiotherapy
Radiotherapy Treatment Approach
Treatment Planning
Dose
Treatment-Related Side Effects
Outcomes
References
Chapter 11: Primary Melanoma and Lentigo Maligna
Indications for Radiotherapy
Primary Melanoma
Desmoplastic Melanoma
Lentigo Maligna
Treatment Planning
Target Volume
Dose Fractionation
Desmoplastic Melanoma
Lentigo Maligna
Palliative Radiotherapy
Treatment-Related Side Effects
References
Chapter 12: Merkel Cell Carcinoma
Indications for Radiotherapy
Adjuvant (Primary Site)
Adjuvant (Regional)
Definitive
Palliative
Treatment Approach
Treatment Planning
Target Volume
Local Treatment
Regional Treatment
Palliative
Dose
Adjuvant
Definitive
Palliative
Treatment-Related Side Effects
Outcomes
Follow-Up
References
Chapter 13: Primary Cutaneous Lymphomas
Introduction
Classification
Epidemiology
Workup
Primary Cutaneous T Cell Lymphoma
Indications for Radiotherapy
Treatment Planning
Target Volume
Examples of Mycosis Fungoides Treatment
Primary Cutaneous B Cell Lymphomas
Indications for Radiotherapy
Treatment Planning
Dose
Outcomes
References
Chapter 14: Regional Radiotherapy in Head and Neck Non-melanoma Skin Cancer
Indications for RT
Adjuvant Nodal RT
Definitive RT
Elective Nodal Radiotherapy
Treatment Strategy/Approach
Treatment Planning
Dose
Regional Radiotherapy in Non-head and Neck Region
Treatment-Related Toxicity and Management
Outcomes
References
Part III: Brachytherapy for Skin Cancer
Chapter 15: Skin Brachytherapy: Overview
Introduction
Indications for BT
Treatment Strategy/Approach
Treatment Margins
Treatment Planning and Dose
Outcomes
References
Part IV: Miscellaneous
Chapter 16: Benign Skin Tumors
Keloid Scars
Treatment Planning
Target Volume
Dose
Treatment-related Side Effects
Outcomes
Keratoacanthoma
Indications for Radiotherapy
Treatment Planning
Target Volume
Dose
Outcomes
References
Chapter 17: Malignant Adnexal Tumors of Skin (MATS)
Indications for Radiotherapy
Treatment Approach
Treatment Planning
Target Volume
Dose
Treatment-related Side Effects
Outcomes
Follow-Up
References
Index