دانلود کتاب RNA Technologies and Their Applications

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Front Matter....Pages i-xvi
The Key Features of RNA Silencing....Pages 1-28
Selected Strategies for the Delivery of siRNA In Vitro and In Vivo ....Pages 29-58
RNAi Suppression and Its Application....Pages 59-92
Strategies to Prevent siRNA-Triggered Cellular Toxicity....Pages 93-106
RNAi in Malignant Brain Tumors: Relevance to Molecular and Translational Research....Pages 107-129
Silencing Huntington’s Disease Gene with RNAi....Pages 131-160
Application of Dicer-Substrate siRNA in Pain Research....Pages 161-190
RNAi Treatment of HIV-1 Infection....Pages 191-208
Application of RNA Interference to Treat Conditions Associated with Dysregulation of Transient Receptor Potential Vanilloid 1 Channel....Pages 209-226
Harnessing RNAi-Based Functional Genomics to Unravel the Molecular Complexity Underlying Skin Pigment Variation....Pages 227-253
mRNA Structure and its Effects on Posttranscriptional Gene Silencing....Pages 255-275
Antisense RNA-Mediated Regulation of the p53 Tumor Suppressor....Pages 277-284
Antisense Oligonucleotides: Insights from Preclinical Studies and Clinical Trials....Pages 285-303
What can the New Hammerhead Ribozyme Structures Teach us About Design?....Pages 305-323
microRNA Biogenesis and its Impact on RNA Interference....Pages 325-354
MicroRNAs in Epithelial Antimicrobial Immunity....Pages 355-367
Emerging Roles of Long Noncoding RNAs in Gene Expression and Intracellular Organization....Pages 369-391
Noncoding RNAs as Therapeutic Targets....Pages 393-418
Noncoding RNAs at H19 / IGF2 Locus: Role in Imprinting, Gene Expression, and Associated Pathologies....Pages 419-443
Back Matter....Pages 445-451