دانلود کتاب The Milan System for Reporting Salivary Gland Cytopathology

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Foreword
Preface
Contents
Contributors
Abbreviations
Chapter 1: The Milan System for Reporting Salivary Gland Cytopathology
Introduction
Format of Report
Indications for Salivary Gland FNA
Sampling Techniques for Salivary Gland FNA
FNA Sample Preparation
FNA Specimen Preparation
References
Chapter 2: Non-Diagnostic
General Background
Definition
Cytologic Criteria
Explanatory Notes (Table 2.1)
Clinical Management
Sample Reports
References
Chapter 3: Non-Neoplastic
General Background
General Definition
Sialolithiasis
Cytologic Criteria
Explanatory Note
Acute Sialadenitis
Cytologic Criteria
Explanatory Notes
Chronic Sialadenitis Including IgG4-Related Disease
Cytologic Criteria
Explanatory Notes
Granulomatous Sialadenitis
Cytologic Criteria
Explanatory Notes
Reactive Lymph Node Hyperplasia
Cytologic Criteria
Explanatory Notes
Benign Lymphoepithelial Lesion/Lymphoepithelial Sialadenitis (LESA)
Cytologic Criteria
Explanatory Notes
Entities Sometimes Classified as “Non-Neoplastic”
Sialadenosis
Cytologic Criteria (Fig. 3.16)
Explanatory Notes
Oncocytosis
Cytologic Criteria
Explanatory Notes
Clinical Management
Sample Reports
References
Chapter 4: Atypia of Undetermined Significance (AUS)
General Background
Definition
Cytologic Criteria
Explanatory Notes
Prevalence and Risk of Malignancy
Management
Sample Reports
References
Chapter 5: Neoplasm
General Background
General Definitions
Benign Neoplasms
Pleomorphic Adenoma (PA) [4, 9, 15–17]
Cytologic Criteria
Explanatory Notes
Warthin Tumor (WT) [4, 14, 15, 17, 18]
Cytologic Criteria
Explanatory Notes
Oncocytoma [21–24]
Cytologic Criteria
Explanatory Notes
Tumors of Mesenchymal Origin
Lipoma [25, 28–30]
Cytologic Criteria (Classic Lipoma)
Explanatory Notes
Schwannoma [34–37]
Cytologic Criteria
Explanatory Notes
Lymphangioma [25, 40, 41]
Cytologic Criteria
Explanatory Notes
Hemangioma [25, 42–44]
Cytologic Criteria
Explanatory Notes
Rare Salivary Gland Mesenchymal Tumors
Explanatory Notes
Salivary Gland Neoplasm of Uncertain Malignant Potential (SUMP)
Cellular Basaloid Neoplasm [24, 51–54]
Cytologic Criteria
Explanatory Notes
Cellular Oncocytic/Oncocytoid Neoplasm [9, 22–24, 53, 56]
Cytologic Criteria (Table 5.3)
Explanatory Notes
Cellular Neoplasm with Clear Cell Features [64–68]
Cytologic Criteria
Explanatory Notes
Clinical Management
Sample Reports
References
Chapter 6: Suspicious for Malignancy
General Background
Definition
Cytologic Criteria
Explanatory Notes
Clinical Management
Sample Reports
References
Chapter 7: Malignant
General Background
Definition
Low-Grade Carcinomas
Acinic Cell Carcinoma (ACC)
Cytologic Criteria
Explanatory Notes
Secretory Carcinoma (SC)
Cytologic Criteria
Explanatory Notes
Epithelial-Myoepithelial Carcinoma (EMC)
Cytologic Criteria
Explanatory Notes
High-Grade Carcinomas
Salivary Duct Carcinoma (SDC)
Cytologic Criteria
Explanatory Notes
Lymphoepithelial Carcinoma (LEC)
Cytologic Criteria
Explanatory Notes
Carcinoma with High-Grade Transformation (HGT)
Small Cell Neuroendocrine Carcinoma (SCNC)
Cytologic Criteria
Explanatory Notes
Cancers with Indeterminate or Multiple Grades
Mucoepidermoid Carcinoma (MEC)
Cytologic Criteria
Explanatory Notes
Adenoid Cystic Carcinoma (AdCC)
Cytologic Criteria
Explanatory Notes
Myoepithelial Carcinoma (MC)
Cytologic Criteria
Explanatory Notes
Carcinoma Ex Pleomorphic Adenoma (CA-ex-PA)
Cytologic Criteria
Explanatory Notes
Hematolymphoid Tumors
Cytologic Criteria
Explanatory Notes
Selected Tumors of Minor Salivary Glands
Polymorphous Adenocarcinoma (PAC)
Cytologic Criteria
Explanatory Notes
Secondary Malignant Tumors
Cytologic Criteria
Explanatory Notes
Malignant Mesenchymal Tumors
Clinical Management
Sample Reports
References
Chapter 8: Ancillary Studies for Salivary Gland Cytology
General Background and Role of Ancillary Studies
Ancillary Techniques for Cytology
Special Stains
Immunochemistry
IC for Basaloid Neoplasms
IC for Oncocytic/Oncocytoid Neoplasms
ICC Markers in Clear Cell Neoplasms
IC for Primary Vs Secondary Salivary Gland Tumors
Molecular Genetic Alterations in Salivary Gland Tumors
Salivary Gland Tumors with Specific Molecular Features
Rarely Encountered Neoplasms of the Minor Salivary Glands with Specific Molecular Features
Fluorescent In Situ Hybridization (FISH)
Polymerase Chain Reaction (PCR)
Next-Generation Sequencing (NGS)
Flow Cytometry (FC)
Summary
Sample Reports
References
Chapter 9: Imaging of the Salivary Glands
Overview of Salivary Gland Imaging: Indications and Modalities
Computed Tomography
Magnetic Resonance Imaging
Ultrasound
Nuclear Scintigraphy and Positron Emission Tomography
Normal Imaging Anatomy of the Major Salivary Glands
Parotid Gland
Submandibular Gland
Sublingual Gland
Imaging Features of Non-neoplastic Conditions
Sialolithiasis
Acute Sialadenitis
Chronic Sialadenitis
Granulomatous Sialadenitis
Reactive Lymph Node
Benign Lymphoepithelial Lesion/Lymphoepithelial Sialadenitis
Sialadenosis
Overview of Imaging for Salivary Gland Neoplasms
Imaging Features of Selected Benign Neoplasms
Pleomorphic Adenoma
Warthin Tumor
Oncocytoma
Lipoma
Imaging Features of Selected Malignant Neoplasms
Mucoepidermoid Carcinoma (MEC)
Adenoid Cystic Carcinoma (AdCC)
Acinic Cell Carcinoma (ACC)
Secretory Carcinoma (SC)
Carcinoma Ex Pleomorphic Adenoma
Lymphoma
Metastases
Image-Guided FNA and Core Biopsy Considerations
References
Chapter 10: Clinical Management
General Background
Clinical Management Considerations: Overview of the Parotid and Submandibular Glands
Management Options by Milan System Diagnostic Category
Category I: Non-Diagnostic
Category II: Non-Neoplastic
Category III: Atypia of Undetermined Significance (AUS)
Category IV: Neoplasm
Category IVA: Benign
Category IVB: Salivary Gland Neoplasm of Uncertain Malignant Potential (SUMP)
Category V: Suspicious for Malignancy
Category VI: Malignant
References
Chapter 11: Histologic Considerations and Salivary Gland Tumor Classification in Surgical Pathology
References
Index