دانلود کتاب RNA and Life Threatening Diseases

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Cover
Title Page
Copyright
ABOUT THE EDITOR
TABLE OF CONTENTS
List of Figures
List of Tables
Abstract
Preface
Chapter 1 Introduction to RNA and Life-Threatening Diseases
1.1 Introduction
1.2 Mutations that Cause Splicing Defects in Disease
1.3 Splicing as a Modifier of Disease Susceptibility
1.4 Splicing Abnormalities in Cancer
1.5 Disruption of Alternative Splicing
1.6 RNAs as Therapeutic Targets and Tools
1.7 RNA Interference
References
Chapter 2 Myotonic Dystrophy Type 2 (DM2)
2.1 Introduction
2.2 Nomenclature
2.3 History
2.4 Aetiology
2.5 Pathogenesis
2.6 Frequency
2.7 Clinical Presentation
2.8 Instrumental Findings
2.9 Diagnosis
2.10 Conclusion
References
Chapter 3 Fragile X- Associated Tremor/Ataxia Syndrome
3.1 Introduction
3.2 Fragile X Syndrome and Associated Disorders
3.3 Epidemiology of FXTAS
3.4 Clinical Presentation of FXTAS
3.5 Neuroradiological Findings
3.6 Pathophysiology
3.7 Diagnosis
3.8 Management and Ongoing Research
3.9 Conclusions
References
Chapter 4 Past, Present, and Future of Arenavirus Taxonomy
4.1 Introduction
4.2 Past Advancements in Arenavirus Taxonomy
4.3 Current Arenavirus Taxonomy
4.4 Nomenclature: Spelling of Arenavirus Species Names
4.5 Solutions to the Present Taxonomic Problems with Arenaviruses
References
Chapter 5 Cardiovascular Disease
5.1 Introduction
5.2 Topology of Disease
5.3 Disease Burden
5.4 Future of Disease
5.5 Cardiovascular Research
5.6 Typology of Research
5.7 High Profile Research
5.8 Future Research Agenda
References
Chapter 6 Neurological Disorders
6.1 Introduction
6.2 A Disease of Alzheimer and Other Dementias
6.3 Epilepsy
References
Chapter 7 Diabetes and Cancer
7.1 Introduction
7.2 Cancer Risk is Increased in Diabetic Patients
7.3 Incidence of Liver and Pancreatic Cancer is Increased in Diabetes
7.4 The Role of Hyperinsulinemia
7.5 Anti-Diabetic Drugs that May Influence Cancer Risk in Diabetic Patients
7.6 Other Factors that May Influence the Risk of Cancer in Diabetes
References
Chapter 8 Blood Diseases
8.1 Introduction
8.2 Anemia
8.3 Leukocytosis
8.4 Polycythemia Vera
8.5 Sickle Cell Disease
8.6 Thalassemia
8.7 Von Willebrand Disease
8.8 Effects of Blood Disorders
8.9 Diagnosis and Tests
References
Index
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